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Slc45a4 Slc45a4 Samt4 Samt4 Nat14 Nat14 Fam71f1 Fam71f1 Atp7a Atp7a Ccdc82 Ccdc82 Atp7b Atp7b Dcdc2b Dcdc2b Zswim4 Zswim4 Mroh5 Mroh5 Dennd3 Dennd3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Slc45a4Solute carrier family 45 member 4; Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family. (785 aa)    
Predicted Functional Partners:
Samt4
Spermatogenesis-associated multipass transmembrane protein 4.
      
 0.540
Nat14
N-acetyltransferase 14; Probable acetyltransferase that binds the 5'-GGACTACAG-3' sequence of coproporphyrinogen oxidase promoter. Able to activate transcription of a reporter construct in vitro (By similarity). Belongs to the camello family.
      
 0.538
Fam71f1
Protein FAM71F1; Belongs to the FAM71 family.
      
 0.523
Atp7a
Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (By similarity); Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
      
 0.513
Ccdc82
Coiled-coil domain-containing protein 82.
      
 0.510
Atp7b
Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
      
 0.486
Dcdc2b
Doublecortin domain-containing 2b.
      
 0.473
Zswim4
Zinc finger SWIM domain-containing protein 4.
   
  
 0.465
Mroh5
Maestro heat-like repeat family member 5.
      
 0.462
Dennd3
DENN domain-containing protein 3; Guanine nucleotide exchange factor (GEF) activating Rab12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab12 into its active GTP-bound form. Regulates autophagy in response to starvation through Rab12 activation. Starvation leads to ULK1/2-dependent phosphorylation of Ser-554 and Ser-572, which in turn allows recruitment of 14-3-3 adapter proteins and leads to up-regulation of GEF activity towards Rab12. Also plays a role in protein transport from recycling endosomes to lysosomes, regulating, for instance, the degradation of the [...]
 
 
  
 0.445
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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