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rnc rnc rpsO rpsO rplS rplS rpmA rpmA rpsI rpsI rplM rplM rpsB rpsB rpsP rpsP rplV rplV rpsL rpsL rpsG rpsG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
rncRNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (276 aa)    
Predicted Functional Partners:
rpsO
SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
 
 0.961
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.947
rpmA
PFAM: ribosomal protein L27; KEGG: sco:SCO2596 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.947
rpsI
PFAM: ribosomal protein S9; KEGG: pac:PPA1802 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.944
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.937
rpsB
PFAM: ribosomal protein S2; KEGG: sco:SCO5624 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.937
rpsP
PFAM: ribosomal protein S16; KEGG: rha:RHA1_ro06535 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.935
rplV
LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
 
 0.931
rpsL
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy.
  
 
 0.930
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
 
 
 0.927
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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