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hemE hemE hemC hemC hemH hemH hemF hemF ABB49178.1 ABB49178.1 ABB50848.1 ABB50848.1 ABB49643.1 ABB49643.1 ABB49279.1 ABB49279.1 ABB50468.1 ABB50468.1 ABB49642.1 ABB49642.1 ABB50664.1 ABB50664.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (346 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
 0.983
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.969
hemF
Coproporphyrinogen oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
 
 0.966
ABB49178.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.948
ABB50848.1
uroporphyrinogen-III C-methyltransferase; Alternative locus ID: P9312_19391; Belongs to the precorrin methyltransferase family.
    
 0.935
ABB49643.1
Conserved hypothetical protein; Alternative locus ID: P9312_06071.
     
 0.832
ABB49279.1
Porphobilinogen synthase; Alternative locus ID: P9312_02251; Belongs to the ALAD family.
 
 
 0.738
ABB50468.1
Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.717
ABB49642.1
Plastocyanin; Alternative locus ID: P9312_06061.
  
    0.702
ABB50664.1
Glutamate synthase (ferredoxin); Alternative locus ID: P9312_17541.
     
 0.655
Your Current Organism:
Prochlorococcus marinus MIT9312
NCBI taxonomy Id: 74546
Other names: P. marinus str. MIT 9312, Prochlorococcus marinus str. MIT 9312, Prochlorococcus sp. MIT 9312, Prochlorococcus sp. MIT9312
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