STRINGSTRING
acxB acxB acxA acxA acxC acxC Xaut_1341 Xaut_1341 Xaut_1339 Xaut_1339 Xaut_1338 Xaut_1338 acxR acxR Xaut_1337 Xaut_1337 Xaut_3460 Xaut_3460
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acxBHydantoinase B/oxoprolinase; Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3- pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide. (776 aa)    
Predicted Functional Partners:
acxA
5-oxoprolinase (ATP-hydrolyzing); Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3- pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.
 0.999
acxC
Acetone carboxylase gamma subunit; Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3- pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.
 
 0.999
Xaut_1341
PFAM: Hydantoinase/oxoprolinase; KEGG: pna:Pnap_1163 5-oxoprolinase (ATP-hydrolyzing).
 
 0.903
Xaut_1339
PFAM: Acetone carboxylase gamma subunit; KEGG: gur:Gura_4361 hypothetical protein.
 
 
 
 0.892
Xaut_1338
PFAM: Hydantoinase/oxoprolinase; KEGG: pna:Pnap_1165 5-oxoprolinase (ATP-hydrolyzing).
 
 0.878
acxR
GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: rpc:RPC_3606 sigma54 specific transcriptional regulator with GAF sensor, fis family.
 
   
 0.680
Xaut_1337
GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: pna:Pnap_1166 GAF modulated sigma54 specific transcriptional regulator, fis family.
 
     0.553
Xaut_3460
ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein; KEGG: pau:PA14_19500 putative sulfonate binding protein.
  
     0.456
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.