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HDHD2 HDHD2 IER3IP1 IER3IP1 KATNAL2 KATNAL2 LHPP LHPP WDR70 WDR70 ELOA3D ELOA3D TMEM267 TMEM267 ELOA3 ELOA3 TTC38 TTC38 ABHD14B ABHD14B LMBRD2 LMBRD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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Experiments
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Textmining
[Homology]
Score
HDHD2Haloacid dehalogenase like hydrolase domain containing 2. (259 aa)    
Predicted Functional Partners:
IER3IP1
Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity); Belongs to the YOS1 family.
   
  
 0.590
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
  
  
 0.532
LHPP
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity); Belongs to the HAD-like hydrolase superfamily.
  
 
0.494
WDR70
WD repeat domain 70; Belongs to the WD repeat GAD-1 family.
   
  
 0.475
ELOA3D
Elongin-A3 member D; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
      
 0.475
TMEM267
Transmembrane protein 267.
   
  
 0.474
ELOA3
Elongin-A3; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
      
 0.446
TTC38
Tetratricopeptide repeat domain 38; Belongs to the TTC38 family.
   
  
 0.443
ABHD14B
Protein ABHD14B; Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription.
  
  
 0.433
LMBRD2
G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family.
   
  
 0.432
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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