STRINGSTRING
Snas_3225 Snas_3225 nth nth Snas_6413 Snas_6413 Snas_2814 Snas_2814 polA polA Snas_0002 Snas_0002 Snas_1102 Snas_1102 ung ung Snas_2021 Snas_2021 Snas_3173 Snas_3173 Snas_3224 Snas_3224
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Snas_3225Exodeoxyribonuclease III Xth; KEGG: bcj:BCAL0487 endonuclease/exonuclease/phosphatase family protein; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. (265 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.980
Snas_6413
Apurinic endonuclease Apn1; KEGG: pca:Pcar_3071 endonuclease IV; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2.
    
 
 0.875
Snas_2814
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: ank:AnaeK_0832 DNA ligase D.
 
 
 0.874
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.862
Snas_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.847
Snas_1102
PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop; KEGG: tgr:Tgr7_2945 A/G-specific DNA-adenine glycosylase.
    
 0.828
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 0.818
Snas_2021
KEGG: hypothetical protein.
  
 0.809
Snas_3173
PFAM: 5'-3' exonuclease; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; KEGG: xau:Xaut_3602 5'-3' exonuclease.
   
 0.804
Snas_3224
PFAM: aminoglycoside phosphotransferase; KEGG: rpt:Rpal_0195 aminoglycoside phosphotransferase.
       0.773
Your Current Organism:
Stackebrandtia nassauensis
NCBI taxonomy Id: 446470
Other names: S. nassauensis DSM 44728, Stackebrandtia nassauensis DSM 44728, Stackebrandtia nassauensis str. DSM 44728, Stackebrandtia nassauensis strain DSM 44728
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.