STRINGSTRING
ADN61970.1 ADN61970.1 ADN57145.1 ADN57145.1 ADN58370.1 ADN58370.1 ADN56270.1 ADN56270.1 ADN61996.1 ADN61996.1 cyaY cyaY ADN60476.1 ADN60476.1 hscB hscB ADN57149.1 ADN57149.1 iscS iscS ADN57146.1 ADN57146.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADN61970.1KEGG: bcj:BCAM0459 cysteine desulfurase; PFAM: aminotransferase class V. (389 aa)    
Predicted Functional Partners:
ADN57145.1
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.998
ADN58370.1
PFAM: SirA-like domain-containing protein; KEGG: SirA family protein; Belongs to the sulfur carrier protein TusA family.
   
 0.980
ADN56270.1
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: bxe:Bxe_A4183 putative molybdopterin biosynthesis protein.
   
 0.977
ADN61996.1
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: bcm:Bcenmc03_6934 UBA/ThiF-type NAD/FAD binding protein.
   
 0.977
cyaY
Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
  
 0.952
ADN60476.1
Rhodanese domain protein; KEGG: bxe:Bxe_B2831 3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
  
 0.922
hscB
Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
 
 
 0.917
ADN57149.1
KEGG: ferredoxin, 2Fe-2S type, ISC system; TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin.
 
 0.913
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
  
 
0.906
ADN57146.1
KEGG: bph:Bphy_1456 iron-sulfur cluster assembly protein IscA; TIGRFAM: iron-sulfur cluster assembly protein IscA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; Belongs to the HesB/IscA family.
 
  
 0.904
Your Current Organism:
Burkholderia sp. CCGE1003
NCBI taxonomy Id: 640512
Other names: B. sp. CCGE1003
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