STRINGSTRING
Kfla_2674 Kfla_2674 Kfla_3726 Kfla_3726 Kfla_5795 Kfla_5795 Kfla_0369 Kfla_0369 Kfla_4392 Kfla_4392 ilvA ilvA trpB trpB trpA trpA Kfla_3519 Kfla_3519 Kfla_4436 Kfla_4436 Kfla_5627 Kfla_5627
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
Kfla_2674PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bcj:BCAM1547 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (123 aa)    
Predicted Functional Partners:
Kfla_3726
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bpy:Bphyt_4303 glyoxalase/bleomycin resistance protein/dioxygenase.
  
 
 
0.919
Kfla_5795
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rle:pRL90064 hypothetical protein.
  
  
  0.918
Kfla_0369
PFAM: beta-lactamase domain protein; KEGG: mrd:Mrad2831_2427 beta-lactamase domain- containing protein.
     
  0.900
Kfla_4392
PFAM: beta-lactamase domain protein; KEGG: dat:HRM2_31220 putative metallo-beta- lactamase family protein.
     
  0.900
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
  0.800
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.800
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
Kfla_3519
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_3768 threonine dehydratase.
     
  0.800
Kfla_4436
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: csa:Csal_0320 L-threonine ammonia-lyase.
     
  0.800
Kfla_5627
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: gsu:GSU0486 threonine dehydratase.
     
  0.800
Your Current Organism:
Kribbella flavida
NCBI taxonomy Id: 479435
Other names: K. flavida DSM 17836, Kribbella flavida DSM 17836, Kribbella flavida str. DSM 17836, Kribbella flavida strain DSM 17836
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