STRINGSTRING
AEU34693.1 AEU34693.1 AEU34692.1 AEU34692.1 prpB prpB acsA acsA AEU38742.1 AEU38742.1 AEU35710.1 AEU35710.1 AEU36292.1 AEU36292.1 AEU37706.1 AEU37706.1 mdh mdh sucC sucC AEU35629.1 AEU35629.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AEU34693.1TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: bcj:BCAM2702 methylcitrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family. (386 aa)    
Predicted Functional Partners:
AEU34692.1
TIGRFAM: 2-methylcitrate dehydratase PrpD; KEGG: bpt:Bpet1812 2-methylcitrate dehydratase; PFAM: MmgE/PrpD.
 
 0.997
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 
 0.982
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.964
AEU38742.1
Aconitate hydratase 1; TIGRFAM: Aconitase/iron regulatory protein 2; KEGG: aca:ACP_2022 aconitate hydratase 1; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel.
 
 0.931
AEU35710.1
TIGRFAM: Methylmalonate-semialdehyde dehydrogenase; KEGG: bid:Bind_0175 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain.
  
 0.930
AEU36292.1
KEGG: azc:AZC_4177 putative aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Belongs to the aldehyde dehydrogenase family.
  
 0.860
AEU37706.1
PFAM: Aldehyde dehydrogenase domain; KEGG: aca:ACP_3483 aldehyde dehydrogenase (NAD) family protein; Belongs to the aldehyde dehydrogenase family.
  
 0.860
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.859
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.851
AEU35629.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: aca:ACP_0089 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase.
 
 
 0.788
Your Current Organism:
Granulicella mallensis
NCBI taxonomy Id: 682795
Other names: G. mallensis MP5ACTX8, Granulicella mallensis MP5ACTX8, Granulicella mallensis str. MP5ACTX8, Granulicella mallensis strain MP5ACTX8, Granulicella sp. MP5ACTX8
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