node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPSL3273 | dnaA | BPSL3273 | BPSL0075 | Putative phosphosugar isomerase; Similar to Pseudomonas aeruginosa probable phosphoheptose isomerase Pa4425 SWALL:Q9HVZ0 (EMBL:AE004857) (197 aa) fasta scores: E(): 3.4e-25, 45.55% id in 191 aa, and to Burkholderia pseudomallei GmhA SWALL:Q93UJ2 (EMBL:AF228583) (197 aa) fasta scores: E(): 6.5e-15, 35.97% id in 189 aa, and to Aneurinibacillus thermoaerophilus sedoheptulose 7-phosphate isomerase GmhA SWALL:Q9AGY7 (EMBL:AF324836) (198 aa) fasta scores: E(): 2.2e-13, 35.75% id in 193 aa. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.682 |
BPSL3273 | gmhA | BPSL3273 | BPSL2795 | Putative phosphosugar isomerase; Similar to Pseudomonas aeruginosa probable phosphoheptose isomerase Pa4425 SWALL:Q9HVZ0 (EMBL:AE004857) (197 aa) fasta scores: E(): 3.4e-25, 45.55% id in 191 aa, and to Burkholderia pseudomallei GmhA SWALL:Q93UJ2 (EMBL:AF228583) (197 aa) fasta scores: E(): 6.5e-15, 35.97% id in 189 aa, and to Aneurinibacillus thermoaerophilus sedoheptulose 7-phosphate isomerase GmhA SWALL:Q9AGY7 (EMBL:AF324836) (198 aa) fasta scores: E(): 2.2e-13, 35.75% id in 193 aa. | Putative sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.918 |
BPSL3405 | dnaA | BPSL3405 | BPSL0075 | Similar to Ralstonia solanacearum putative chromosome partitioning protein ParB or Rsc3325 or Rs02555 SWALL:Q8XU68 (EMBL:AL646074) (303 aa) fasta scores: E(): 2.3e-72, 73.12% id in 294 aa, and to Caulobacter crescentus chromosome partitioning protein ParB or Cc3752 SWALL:PARB_CAUCR (SWALL:O05190) (294 aa) fasta scores: E(): 3.8e-32, 42.42% id in 297 aa; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.841 |
BPSL3405 | dnaN | BPSL3405 | BPSL0074 | Similar to Ralstonia solanacearum putative chromosome partitioning protein ParB or Rsc3325 or Rs02555 SWALL:Q8XU68 (EMBL:AL646074) (303 aa) fasta scores: E(): 2.3e-72, 73.12% id in 294 aa, and to Caulobacter crescentus chromosome partitioning protein ParB or Cc3752 SWALL:PARB_CAUCR (SWALL:O05190) (294 aa) fasta scores: E(): 3.8e-32, 42.42% id in 297 aa; Belongs to the ParB family. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.702 |
BPSL3405 | recR | BPSL3405 | BPSL1500 | Similar to Ralstonia solanacearum putative chromosome partitioning protein ParB or Rsc3325 or Rs02555 SWALL:Q8XU68 (EMBL:AL646074) (303 aa) fasta scores: E(): 2.3e-72, 73.12% id in 294 aa, and to Caulobacter crescentus chromosome partitioning protein ParB or Cc3752 SWALL:PARB_CAUCR (SWALL:O05190) (294 aa) fasta scores: E(): 3.8e-32, 42.42% id in 297 aa; Belongs to the ParB family. | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.572 |
BPSS1680 | dnaA | BPSS1680 | BPSL0075 | Putative histone-like protein; Similar to Bordetella pertussis Bph2 SWALL:P94344 (EMBL:U82555) (145 aa) fasta scores: E(): 3.7e-26, 65.27% id in 144 aa, and to Xylella fastidiosa histone-like protein xf1943 SWALL:Q9PC42 (EMBL:AE004013) (130 aa) fasta scores: E(): 1.2e-18, 54.61% id in 130 aa; Belongs to the bacterial histone-like protein family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.816 |
dnaA | BPSL3273 | BPSL0075 | BPSL3273 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Putative phosphosugar isomerase; Similar to Pseudomonas aeruginosa probable phosphoheptose isomerase Pa4425 SWALL:Q9HVZ0 (EMBL:AE004857) (197 aa) fasta scores: E(): 3.4e-25, 45.55% id in 191 aa, and to Burkholderia pseudomallei GmhA SWALL:Q93UJ2 (EMBL:AF228583) (197 aa) fasta scores: E(): 6.5e-15, 35.97% id in 189 aa, and to Aneurinibacillus thermoaerophilus sedoheptulose 7-phosphate isomerase GmhA SWALL:Q9AGY7 (EMBL:AF324836) (198 aa) fasta scores: E(): 2.2e-13, 35.75% id in 193 aa. | 0.682 |
dnaA | BPSL3405 | BPSL0075 | BPSL3405 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Similar to Ralstonia solanacearum putative chromosome partitioning protein ParB or Rsc3325 or Rs02555 SWALL:Q8XU68 (EMBL:AL646074) (303 aa) fasta scores: E(): 2.3e-72, 73.12% id in 294 aa, and to Caulobacter crescentus chromosome partitioning protein ParB or Cc3752 SWALL:PARB_CAUCR (SWALL:O05190) (294 aa) fasta scores: E(): 3.8e-32, 42.42% id in 297 aa; Belongs to the ParB family. | 0.841 |
dnaA | BPSS1680 | BPSL0075 | BPSS1680 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Putative histone-like protein; Similar to Bordetella pertussis Bph2 SWALL:P94344 (EMBL:U82555) (145 aa) fasta scores: E(): 3.7e-26, 65.27% id in 144 aa, and to Xylella fastidiosa histone-like protein xf1943 SWALL:Q9PC42 (EMBL:AE004013) (130 aa) fasta scores: E(): 1.2e-18, 54.61% id in 130 aa; Belongs to the bacterial histone-like protein family. | 0.816 |
dnaA | dnaB | BPSL0075 | BPSL1462 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.948 |
dnaA | dnaN | BPSL0075 | BPSL0074 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.995 |
dnaA | dnaX | BPSL0075 | BPSL1498 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III subunit gamma; Similar to the N-terminal region of Escherichia coli DNA polymerase III subunit tau DnaX or DnaZ or DnaZX or b0470 SWALL:DP3X_ECOLI (SWALL:P06710) (643 aa) fasta scores: E(): 1.4e-51, 46.7% id in 531 aa, and to the N-terminal region of Ralstonia solanacearum probable DNA polymerase III rsc1191 or rs05723 SWALL:Q8Y053 (EMBL:AL646063) (728 aa) fasta scores: E(): 9e-82, 54.42% id in 836 aa, and to the full length of Buchnera aphidicola DNA polymerase III subunit gamma DnaX or bu481 SWALL:DP3X_BUCAI (SWALL:P57553) (361 aa) fasta scores: E(): 4.4e-34, 42.22 [...] | 0.716 |
dnaA | gmhA | BPSL0075 | BPSL2795 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Putative sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.682 |
dnaA | gyrB | BPSL0075 | BPSL0073 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.699 |
dnaA | recR | BPSL0075 | BPSL1500 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.769 |
dnaA | ruvA | BPSL0075 | BPSL2898 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.682 |
dnaB | dnaA | BPSL1462 | BPSL0075 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.948 |
dnaB | dnaN | BPSL1462 | BPSL0074 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.651 |
dnaB | dnaX | BPSL1462 | BPSL1498 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III subunit gamma; Similar to the N-terminal region of Escherichia coli DNA polymerase III subunit tau DnaX or DnaZ or DnaZX or b0470 SWALL:DP3X_ECOLI (SWALL:P06710) (643 aa) fasta scores: E(): 1.4e-51, 46.7% id in 531 aa, and to the N-terminal region of Ralstonia solanacearum probable DNA polymerase III rsc1191 or rs05723 SWALL:Q8Y053 (EMBL:AL646063) (728 aa) fasta scores: E(): 9e-82, 54.42% id in 836 aa, and to the full length of Buchnera aphidicola DNA polymerase III subunit gamma DnaX or bu481 SWALL:DP3X_BUCAI (SWALL:P57553) (361 aa) fasta scores: E(): 4.4e-34, 42.22 [...] | 0.863 |
dnaB | recR | BPSL1462 | BPSL1500 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.748 |