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gshA-2 gshA-2 gshB gshB BPSL0001 BPSL0001 PepN PepN BPSL3089 BPSL3089 pepA pepA BPSL0416 BPSL0416 BPSL0692 BPSL0692 BPSS1288 BPSS1288 pxpA1 pxpA1 BPSL0258 BPSL0258
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshA-2Similar to Escherichia coli glutamate--cysteine ligase GshA or Gsh-I SWALL:GSH1_ECOLI (SWALL:P06980) (518 aa) fasta scores: E(): 2.1e-70, 41.74% id in 515 aa, and to Pseudomonas aeruginosa glutamate--cysteine ligase pa5203 SWALL:Q9HTY6 (EMBL:AE004933) (527 aa) fasta scores: E(): 1.3e-117, 59.73% id in 529 aa; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (533 aa)    
Predicted Functional Partners:
gshB
Similar to Escherichia coli glutathione synthetase GshB or Gsh-II SWALL:GSHB_ECOLI (SWALL:P04425) (316 aa) fasta scores: E(): 3.4e-53, 48.22% id in 309 aa, and to Ralstonia solanacearum glutathione synthetase rsc0345 or rs03312 SWALL:GSHB_RALSO (SWALL:P58579) (324 aa) fasta scores: E(): 2.8e-80, 68.43% id in 320 aa; Belongs to the prokaryotic GSH synthase family.
  
 
 0.933
BPSL0001
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
 0.915
PepN
Alanyl aminopeptidase; Similar to Ralstonia solanacearum probable aminopeptidase N PepN or rsc2125 or rs01479 SWALL:Q8XXI8 (EMBL:AL646068) (905 aa) fasta scores: E(): 1.1e-170, 66.11% id in 906 aa and to Escherichia coli aminopeptidase N PepN or b0932 SWALL:AMPN_ECOLI (SWALL:P04825) (869 aa) fasta scores: E(): 9.5e-101, 48.6% id in 897 aa.
     
 0.911
BPSL3089
Family M1 unassigned peptidase; Similar to Ralstonia solanacearum putative aminopeptidase transmembrane protein Rsp0532 or Rs00411 SWALL:Q8XSE4 (EMBL:AL646079) (748 aa) fasta scores: E(): 2.4e-99, 46.99% id in 749 aa, and to Mus musculus puromycin-sensitive aminopeptidase Psa SWALL:PSA_MOUSE (SWALL:Q11011) (920 aa) fasta scores: E(): 8e-34, 27.5% id in 629 aa, and to Lactobacillus helveticus aminopeptidase N PepN SWALL:AMPN_LACHE (SWALL:Q10730) (844 aa) fasta scores: E(): 1.1e-25, 30.13% id in 511 aa.
     
 0.911
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.910
BPSL0416
Zinc-binding dehydrogenase (fragment); PS00228 Tubulin-beta mRNA autoregulation signal.
    
  0.907
BPSL0692
Gamma-glutamyltransferase 2; Similar to Ralstonia solanacearum putative gamma-glutamyltranspeptidase protein rsc2501 or rs01094 SWALL:Q8XWH3 (EMBL:AL646070) (552 aa) fasta scores: E(): 8.6e-156, 70.73% id in 557 aa, and to Deinococcus radiodurans cephalosporin acylase dr1524 SWALL:Q9RU70 (EMBL:AE001996) (535 aa) fasta scores: E(): 5.2e-90, 50.64% id in 547 aa, and to Bacillus halodurans cephalosporin acylase bh0867 SWALL:Q9KEI5 (EMBL:AP001510) (539 aa) fasta scores: E(): 3.7e-89, 49.36% id in 547 aa; possible alternative start site at codon 4.
    
  0.907
BPSS1288
Gamma-glutamyltransferase 1; Similar to Helicobacter pylori gamma-glutamyltranspeptidase hp1118 SWALL:O25743 (EMBL:AE000618) (567 aa) fasta scores: E(): 1.3e-83, 42.43% id in 568 aa, and to Caulobacter crescentus gamma-glutamyltransferase cc0104 SWALL:Q9ABW6 (EMBL:AE005685) (583 aa) fasta scores: E(): 3.3e-132, 63.54% id in 565 aa, and to Pseudomonas aeruginosa gamma-glutamyltranspeptidase precursor Ggt or pa1338 SWALL:Q9I406 (EMBL:AE004563) (557 aa) fasta scores: E(): 3.2e-130, 63.04% id in 552 aa.
    
  0.907
pxpA1
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
BPSL0258
Similar to Ralstonia solanacearum hypothetical protein rsc2170 or rs01429 SWALL:Q8XXE4 (EMBL:AL646068) (353 aa) fasta scores: E(): 3.2e-32, 54.44% id in 360 aa, and to an internal region of Saccharomyces cerevisiae urea amidolyase [includes: urea carboxylase; allophanate hydrolase] DUR1,2 SWALL:DUR1_YEAST (SWALL:P32528) (1835 aa) fasta scores: E(): 2.4e-15, 32.19% id in 351 aa.
     
  0.900
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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