STRINGSTRING
argB argB argJ argJ argC argC argA argA argG-2 argG-2 argD argD argG argG argH argH argM argM argF argF glnB1 glnB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argBPutative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)    
Predicted Functional Partners:
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 0.998
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
 
 0.997
argA
Putative amino-acid acetyltransferase; Similar to Escherichia coli, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.5e-76, 46.89% id in 435 aa, and to Ralstonia solanacearum probable amino-acid acetyltransferase protein rsc1250 or rs02762 SWALL:Q8XZZ5 (EMBL:AL646063) (451 aa) fasta scores: E(): 3.6e-123, 71.71% id in 449 aa. CDS is extended at the N-terminus in comparison to some orthologues. Possible alternative translational start site.
 
 
0.993
argG-2
Similar to Streptomyces clavuligerus argininosuccinate synthase ArgG SWALL:ASSY_STRCL (SWALL:P50986) (397 aa) fasta scores: E(): 8.4e-49, 35.78% id in 394 aa, and to Thermoanaerobacter tengcongensis argininosuccinate synthase tte2494 SWALL:Q8R7C2 (EMBL:AE013190) (410 aa) fasta scores: E(): 1.9e-70, 44.92% id in 394 aa.
 
  
 0.899
argD
Aminotransferase class-III; Similar to Synechocystis sp. acetylornithine aminotransferase ArgD or slr1022 SWALL:ARGD_SYNY3 (SWALL:P73133) (429 aa) fasta scores: E(): 4.2e-52, 41.44% id in 415 aa, and to Ralstonia solanacearum putative succinylornithine transaminase and acetylornithine aminotransferase protein ArgM or rsc2435 or rs02668 SWALL:Q8XWN8 (EMBL:AL646070) (399 aa) fasta scores: E(): 3.4e-121, 77.97% id in 395 aa, and to Pseudomonas aeruginosa probable class III pyridoxal phosphate-dependent aminotransferase pa0530 SWALL:Q9I606 (EMBL:AE004489) (393 aa) fasta scores: E(): 1.3e-6 [...]
 
  
 0.891
argG
Similar to Escherichia coli argininosuccinate synthase ArgG SWALL:ASSY_ECOLI (SWALL:P22767) (446 aa) fasta scores: E(): 1.1e-138, 77.87% id in 443 aa, and to Neisseria meningitidis argininosuccinate synthase nma0303 SWALL:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 1.2e-144, 82.87% id in 438 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
  
 0.852
argH
Similar to Escherichia coli argininosuccinate lyase ArgH or b3960 SWALL:ARLY_ECOLI (SWALL:P11447) (457 aa) fasta scores: E(): 9.8e-72, 44.97% id in 458 aa, to Pseudomonas aeruginosa argininosuccinate lyase ArgH or pa5263 SWALL:ARLY_PSEAE (SWALL:P50987) (464 aa) fasta scores: E(): 1.5e-110, 64.51% id in 465 aa, and to Ralstonia solanacearum argininosuccinate lyase rsc2363 or rs01183 SWALL:ARLY_RALSO (SWALL:Q8XWV7) (471 aa) fasta scores: E(): 1.5e-143, 82.09% id in 469 aa.
 
  
 0.845
argM
Similar to Escherichia coli succinylornithine transaminase ArgM or AstC or CstC SWALL:ARGM_ECOLI (SWALL:P77581) (406 aa) fasta scores: E(): 5.3e-93, 61.38% id in 404 aa, and to Vibrio cholerae acetylornithine aminotransferase vc2618 SWALL:Q9KNW2 (EMBL:AE004328) (403 aa) fasta scores: E(): 1.4e-94, 60.55% id in 398 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.839
argF
Putative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
  
 0.832
glnB1
Similar to Klebsiella pneumoniae nitrogen regulatory protein P-II GlnB SWALL:GLNB_KLEPN (SWALL:P11671) (112 aa) fasta scores: E(): 2.2e-26, 70.53% id in 112 aa, and to Ralstonia solanacearum probable nitrogen regulatory P-II transcription regulator protein rsc0342 or rs06099 SWALL:Q8Y2J3 (EMBL:AL646058) (112 aa) fasta scores: E(): 1.1e-32, 84.82% id in 112 aa. Similar to BPSL1027, 75.000% identity (75.000% ungapped) in 112 aa overlap; Belongs to the P(II) protein family.
  
 
 
 0.817
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.