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xerC xerC BPSL0209 BPSL0209 dapF dapF BPSL3344 BPSL3344 BPSL1109 BPSL1109 BPSL2604 BPSL2604 BPSL0207 BPSL0207 BPSL3405 BPSL3405 BPSL0211 BPSL0211 recR recR dnaA dnaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
xerCIntegrase/recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (310 aa)    
Predicted Functional Partners:
BPSL0209
Similar to Ralstonia solanacearum hypothetical protein rsc0053 or rs01876 SWALL:Q8Y3C7 (EMBL:AL646057) (237 aa) fasta scores: E(): 1.2e-43, 53.3% id in 242 aa, and to Pseudomonas fluorescens hypothetical protein SWALL:O05323 (EMBL:Y12268) (240 aa) fasta scores: E(): 2.9e-06, 29.15% id in 247 aa.
 
    0.850
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
  
 0.829
BPSL3344
Similar to Bacteriophage D3 integrase orf35 SWALL:Q9T1P3 (EMBL:AF165214) (369 aa) fasta scores: E(): 2.9e-44, 44.8% id in 279 aa, and to Escherichia coli prophage Dlp12 integrase IntD or Int or b0537 SWALL:INTD_ECOLI (SWALL:P24218) (387 aa) fasta scores: E(): 3.3e-18, 36.64% id in 191 aa; Belongs to the 'phage' integrase family.
  
 
 
 0.771
BPSL1109
Putative membrane protein; C-terminal region similar to Escherichia coli cell division protein FtsK or b0890 SWALL:FTSK_ECOLI (SWALL:P46889) (1329 aa) fasta scores: E(): 3.4e-64, 39.91% id in 1125 aa, and N-terminal region to Streptococcus pneumoniae cell wall surface anchor family protein sp1772 SWALL:Q97P71 (EMBL:AE007470) (4776 aa) fasta scores: E(): 3.1e-25, 26.32% id in 1189 aa. Note: Also contains a repeat region (7x TSAET(A/V)AP(D/N)(D/G/S)H(A/V)(P/S)); Belongs to the FtsK/SpoIIIE/SftA family.
  
   
 0.681
BPSL2604
Similar to many involved in cell-division or sporulation: Coxiella burnetii cell division protein FtsK homolog or spoIIIE SWALL:FTSK_COXBU (SWALL:P39920) (778 aa) fasta scores: E(): 5.2e-130, 50.06% id in 765 aa, and to Ralstonia solanacearum probable cell division FtsK transmembrane protein or rsc2341 or rs01205 SWALL:Q8XWX9 (EMBL:AL646069) (781 aa) fasta scores: E(): 4.3e-202, 71.02% id in 780 aa.
  
   
 0.655
BPSL0207
Similar to Ralstonia solanacearum hypothetical protein rsc0051 or rs01874 SWALL:Q8Y3C9 (EMBL:AL646057) (397 aa) fasta scores: E(): 2.2e-80, 71.46% id in 424 aa, and to Yersinia pestis hypothetical protein YPO1445 SWALL:Q8ZG67 (EMBL:AJ414148) (396 aa) fasta scores: E(): 3.7e-45, 41.33% id in 421 aa.
       0.609
BPSL3405
Similar to Ralstonia solanacearum putative chromosome partitioning protein ParB or Rsc3325 or Rs02555 SWALL:Q8XU68 (EMBL:AL646074) (303 aa) fasta scores: E(): 2.3e-72, 73.12% id in 294 aa, and to Caulobacter crescentus chromosome partitioning protein ParB or Cc3752 SWALL:PARB_CAUCR (SWALL:O05190) (294 aa) fasta scores: E(): 3.8e-32, 42.42% id in 297 aa; Belongs to the ParB family.
  
   
 0.605
BPSL0211
Similar to Escherichia coli lipid A biosynthesis lauroyl acyltransferase HtrB or WaaM SWALL:HTRB_ECOLI (SWALL:P24187) (306 aa) fasta scores: E(): 7.4e-31, 34.7% id in 291 aa, and to Ralstonia solanacearum putative acyltransferase protein rsc0136 or rs01006 SWALL:Q8Y345 (EMBL:AL646057) (297 aa) fasta scores: E(): 5.2e-56, 47.29% id in 296 aa.
     
 0.580
recR
Recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.551
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
  
   
 0.546
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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