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BPSL0390 BPSL0390 BPSL2738 BPSL2738 BPSS1019 BPSS1019 BPSL0513 BPSL0513 BPSL3239 BPSL3239 fumC fumC BPSS1720 BPSS1720 sdhA sdhA sdhB sdhB sdhB-2 sdhB-2 BPSS1719 BPSS1719
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSL0390Fumarylacetoacetate (FAA) hydrolase family protein; Similar to Ralstonia solanacearum hypothetical protein rsc0301 or rs03268 SWALL:Q8Y2N4 (EMBL:AL646058) (330 aa) fasta scores: E(): 5.7e-101, 76.22% id in 328 aa, and to Xanthomonas campestris putative dioxygenase xcc0591 SWALL:AAM39907 (EMBL:AF204145) (329 aa) fasta scores: E(): 6e-75, 60.99% id in 323 aa. (330 aa)    
Predicted Functional Partners:
BPSL2738
Putative hydrolase; Similar to Prokaryotic and Eukaryotic hydrolases including: Ralstonia solanacearum probable fumarylacetoacetase rsp0690 or rs01759 SWALL:Q8XRZ1 (EMBL:AL646080) (423 aa) fasta scores: E(): 7.1e-116, 69.23% id in 416 aa and to Homo sapiens fumarylacetoacetase Fah SWALL:FAAA_HUMAN (SWALL:P16930) (419 aa) fasta scores: E(): 2.1e-99, 57.17% id in 411 aa.
     
 0.904
BPSS1019
Similar to Ralstonia sp. U2 fumarylpyruvate hydrolase nagK SWALL:O86042 (EMBL:AF036940) (192 aa) fasta scores: E(): 3.5e-23, 40.2% id in 194 aa, and to Rhizobium loti hypothetical protein Mlr1134 mlr1134 SWALL:Q98L86 (EMBL:AP002996) (232 aa) fasta scores: E(): 1.4e-57, 63.04% id in 230 aa, and to Ralstonia solanacearum hypothetical protein rsc0383 rsc0383 or rs03351 SWALL:Q8Y2F3 (EMBL:AL646059) (233 aa) fasta scores: E(): 1.2e-48, 55.6% id in 232 aa.
     
  0.900
BPSL0513
Similar to Homo sapiens maleylacetoacetate isomerase GSTZ1 or MAAI SWALL:MAAI_HUMAN (SWALL:O43708) (216 aa) fasta scores: E(): 2.5e-31, 47.39% id in 211 aa, and to Ralstonia solanacearum probable maleylacetoacetate isomerase rsc0384 or rs03352 SWALL:Q8Y2F2 (EMBL:AL646059) (216 aa) fasta scores: E(): 3.5e-54, 63.38% id in 213 aa.
 
 
 0.895
BPSL3239
Similar to Pseudomonas sp. 4-hydroxyphenylpyruvate dioxygenase SWALL:HPPD_PSESP (SWALL:P80064) (357 aa) fasta scores: E(): 5.7e-37, 57.89% id in 361 aa.
 
  
 0.849
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.830
BPSS1720
Similar to Ralstonia solanacearum putative transmembrane succinate dehydrogenase SdhC or rsc1996 or rs03564 SWALL:Q8XXW7 (EMBL:AL646067) (140 aa) fasta scores: E(): 1.1e-30, 58.69% id in 138 aa, and to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 7.3e-11, 35.15% id in 128 aa.
  
 
  0.827
sdhA
Succinate dehydrogenase flavoprotein subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 succinate dehydrogenase flavoprotein subunit SdhA or b0723 or c0801 or z0877 or ecs0748 SWALL:DHSA_ECOLI (SWALL:P10444) (588 aa) fasta scores: E(): 7.9e-127, 55.46% id in 586 aa, and to Ralstonia solanacearum putative succinate dehydrogenase SdhA or rsc1994 or rs03562 SWALL:Q8XXW9 (EMBL:AL646067) (592 aa) fasta scores: E(): 6.1e-201, 85.3% id in 592 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.824
sdhB
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or b0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 5.9e-65, 66.81% id in 232 aa, and to Ralstonia solanacearum putative succinate dehydrogenase rsc1993 or rs03561 SWALL:Q8XXX0 (EMBL:AL646067) (233 aa) fasta scores: E(): 5.5e-89, 90.51% id in 232 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.807
sdhB-2
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 3.3e-63, 63.79% id in 232 aa, and to Ralstonia solanacearum putative succinate dehydrogenase rsc1993 or rs03561 SWALL:Q8XXX0 (EMBL:AL646067) (233 aa) fasta scores: E(): 1.7e-74, 73.16% id in 231 aa. Similar to BPSS1717, 74.459% identity (74.783% ungapped) in 231 aa overlap.
  
 
  0.807
BPSS1719
Putative succinate dehydrogenase; Similar to Ralstonia solanacearum putative transmembrane succinate dehydrogenase sdhd or rsc1995 or rs03563 SWALL:Q8XXW8 (EMBL:AL646067) (121 aa) fasta scores: E(): 1.2e-35, 71.31% id in 122 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri succinate dehydrogenase hydrophobic membrane anchor protein sdhd or b0722 or c0800 or sf0575 SWALL:DHSD_ECOLI (SWALL:P10445) (115 aa) fasta scores: E(): 1.7e-10, 32.69% id in 104 aa.
   
 
  0.805
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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