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LolB LolB BPSL0525 BPSL0525 ispE ispE BPSL0505 BPSL0505 minE minE mutY mutY BPSL2724 BPSL2724 BPSL1017 BPSL1017 mutM mutM lolA lolA BPSL1902 BPSL1902
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
LolBPutative lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (207 aa)    
Predicted Functional Partners:
BPSL0525
Putative membrane protein; Similar to Ralstonia solanacearum hypothetical transmembrane protein rsc0398 or rs03366 SWALL:Q8Y2D8 (EMBL:AL646059) (642 aa) fasta scores: E(): 2.2e-43, 41.42% id in 630 aa> C-terminus is similar to the C-terminal region of Pseudomonas aeruginosa hypothetical protein pa4667 SWALL:YAG7_PSEAE (SWALL:P42810) (590 aa) fasta scores: E(): 1.7e-38, 30.1% id in 558 aa.
 
    0.929
ispE
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
    0.756
BPSL0505
Putative exported protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.
 
  
 0.743
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.697
mutY
Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
     0.660
BPSL2724
Putative TonB-dependent outer-membrane receptor protein; Similar to Xanthomonas axonopodis TonB-dependent receptor FhuA or xac4062 SWALL:Q8PFC1 (EMBL:AE012054) (726 aa) fasta scores: E(): 8.7e-33, 30.99% id in 742 aa, Anabaena sp. ferrichrome-iron receptor all2148 SWALL:Q8YV33 (EMBL:AP003588) (863 aa) fasta scores: E(): 5.7e-28, 26.62% id in 725 aa and to Salmonella typhimurium ferrioxamine B receptor precursor FoxA or Stm0364 SWALL:FOXA_SALTY (SWALL:Q56145) (702 aa) fasta scores: E(): 7.4e-23, 24.6% id in 687 aa.
      
 0.628
BPSL1017
Putative porphyrin biosynthesis related protein; Similar to Escherichia coli, and Escherichia coli O157:H7 HemY protein or b3802 or z5316 or ecs4732 SWALL:HEMY_ECOLI (SWALL:P09128) (398 aa) fasta scores: E(): 3.8e-08, 23.27% id in 391 aa, and to Ralstonia solanacearum putative protein porphyrin biosynthesis rsc2355 or rs01191 SWALL:Q8XWW5 (EMBL:AL646069) (397 aa) fasta scores: E(): 2e-69, 50.63% id in 393 aa.
 
     0.620
mutM
Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.614
lolA
Probable outer-membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
 
 
 0.588
BPSL1902
Putative membrane protein; Similar to Ralstonia solanacearum putative hemagglutinin-related transmembrane protein rsp1094 or rs02600 SWALL:Q8XQX4 (EMBL:AL646082) (459 aa) fasta scores: E(): 6.2e-32, 43.89% id in 426 aa. Note: Also similar to BPSL1901 (558 aa) fasta scores: E(): 1.6e-34, 45.366% identity in 410 aa overlap.
  
     0.582
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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