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aspS aspS gatB gatB hisS hisS valS valS gatC gatC pheT pheT guaA guaA alaS alaS NtpA NtpA glnS glnS metG metG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (598 aa)    
Predicted Functional Partners:
gatB
glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
 
 
 0.993
hisS
histidyl-tRNA synthetase; Similar to Escherichia coli, and Escherichia coli O157:H7 histidyl-tRNA synthetase HisS or b2514 or z3777 or ecs3376 SWALL:SYH_ECOLI (SWALL:P04804) (423 aa) fasta scores: E(): 1.2e-82, 54.52% id in 420 aa, and to Ralstonia solanacearum probable histidine-tRNA synthetase protein HisS or rsc1216 or rs02790 SWALL:Q8Y029 (EMBL:AL646063) (432 aa) fasta scores: E(): 1e-130, 75.4% id in 435 aa.
 
  
 0.952
valS
Putative valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
  
 0.909
gatC
glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
 
 0.887
pheT
Similar to Escherichia coli phenylalanyl-tRNA synthetase beta chain PheT or b1713 SWALL:SYFB_ECOLI (SWALL:P07395) (795 aa) fasta scores: E(): 3.2e-119, 41.84% id in 815 aa, and to Ralstonia solanacearum probable phenylalanyl-tRNA synthetase beta chain protein rsc1582 or rs05825 SWALL:Q8XZ24 (EMBL:AL646065) (809 aa) fasta scores: E(): 0, 67.53% id in 810 aa.
  
  
 0.838
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.824
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
  
 0.809
NtpA
Similar to Escherichia coli dATP pyrophosphohydrolase NudB or NtpA SWALL:NUDB_ECOLI (SWALL:P24236) (150 aa) fasta scores: E(): 8.2e-16, 44.82% id in 145 aa, and to Ralstonia solanacearum probable datp pyrophosphohydrolase protein rsc0468 or rs04429 SWALL:Q8Y268 (EMBL:AL646059) (162 aa) fasta scores: E(): 8.4e-36, 64.55% id in 158 aa.
  
   0.770
glnS
Similar to Escherichia coli glutaminyl-tRNA synthetase GlnS or b0680 SWALL:SYQ_ECOLI (SWALL:P00962) (553 aa) fasta scores: E(): 9.9e-131, 57.34% id in 558 aa, and to Ralstonia solanacearum glutaminyl-tRNA synthetase rsc0791 or rs05046 SWALL:Q8Y199 (EMBL:AL646061) (580 aa) fasta scores: E(): 1.9e-175, 70.35% id in 570 aa.
  
  
 0.764
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.756
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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