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BPSL0666 BPSL0666 wcbL wcbL BPSL0395 BPSL0395 waaE waaE gmhA gmhA wcbM wcbM wcbN wcbN BPSL3273 BPSL3273 waaF waaF glyS glyS BPSS0425 BPSS0425
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSL0666Putative hydrolase/phosphatase protein; Similar to Pseudomonas fluorescens hisB-like protein SWALL:Q9F729 (EMBL:AF286536) (213 aa) fasta scores: E(): 1e-33, 54.85% id in 175 aa, and to Ralstonia solanacearum putative phosphatase protein rsc0523 or rs04957 SWALL:Q8Y214 (EMBL:AL646059) (199 aa) fasta scores: E(): 7.2e-49, 72.62% id in 179 aa, and to Neisseria meningitidis putative phosphatase nma0405 SWALL:Q9JWE9 (EMBL:AL162753) (187 aa) fasta scores: E(): 2.5e-36, 56.98% id in 179 aa. (187 aa)    
Predicted Functional Partners:
wcbL
Putative sugar kinase; Similar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 7-phosphate kinase GmhB SWALL:Q9AGY8 (EMBL:AF324836) (341 aa) fasta scores: E(): 1.6e-79, 55.84% id in 342 aa. Previously sequenced Burkholderia pseudomallei putative sugar kinase WcbL SWALL:Q93UJ3 (EMBL:AF228583) (346 aa) fasta scores: E(): 5.3e-139, 100% id in 346 aa.
 
 
 0.993
BPSL0395
Putative cytidylyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
  
 0.991
waaE
Putative ADP-heptose synthase; Previously sequenced as Burkholderia pseudomallei putative ADP-heptose synthase WaaE SWALL:Q9WWX7 (EMBL:AF159428) (307 aa) fasta scores: E(): 3.8e-113, 100% id in 307 aa, and to Haemophilus influenzae ADP-heptose synthase RfaE or WaaE or hi1526 SWALL:RFAE_HAEIN (SWALL:O05074) (476 aa) fasta scores: E(): 9.1e-47, 49% id in 302 aa and to Escherichia coli ADP-heptose synthase RfaE or waae or b3052 SWALL:RFAE_ECOLI (SWALL:P76658) (477 aa) fasta scores: E(): 8.8e-46, 49.19% id in 309 aa.
 
  
 0.978
gmhA
Putative sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
  
 0.977
wcbM
Similar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 1-phosphate guanosyltransferase GmhD SWALL:Q9AGY6 (EMBL:AF324836) (230 aa) fasta scores: E(): 4.6e-29, 39.55% id in 225 aa. Previously sequenced Burkholderia pseudomallei putative capsular polysaccharide biosynthesis protein WcbM SWALL:Q93UJ1 (EMBL:AF228583) (230 aa) fasta scores: E(): 5e-89, 99.56% id in 230 aa.
 0.964
wcbN
Similar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase GmhC SWALL:Q9AGY5 (EMBL:AF324836) (179 aa) fasta scores: E(): 3.6e-35, 60% id in 155 aa. Identical to Burkholderia mallei WcbN protein SWALL:Q9AI34 (EMBL:AF285636) (189 aa) fasta scores: E(): 9.5e-78, 100% id in 189 aa.
  
  
 
0.923
BPSL3273
Putative phosphosugar isomerase; Similar to Pseudomonas aeruginosa probable phosphoheptose isomerase Pa4425 SWALL:Q9HVZ0 (EMBL:AE004857) (197 aa) fasta scores: E(): 3.4e-25, 45.55% id in 191 aa, and to Burkholderia pseudomallei GmhA SWALL:Q93UJ2 (EMBL:AF228583) (197 aa) fasta scores: E(): 6.5e-15, 35.97% id in 189 aa, and to Aneurinibacillus thermoaerophilus sedoheptulose 7-phosphate isomerase GmhA SWALL:Q9AGY7 (EMBL:AF324836) (198 aa) fasta scores: E(): 2.2e-13, 35.75% id in 193 aa.
 
  
 0.893
waaF
Putative ADP-heptose--LPS heptosyltransferase II; Previously sequenced as Burkholderia pseudomallei heptosyl transferase WaaF SWALL:Q9ZFN3 (EMBL:AF097748) (346 aa) fasta scores: E(): 6.5e-139, 99.42% id in 346 aa. Similar to Escherichia coli ADP-heptose--LPS heptosyltransferase II RfaF or Waaf SWALL:RFAF_ECOLI (SWALL:P37692) (348 aa) fasta scores: E(): 1.8e-49, 44.03% id in 352 aa.
   
 0.764
glyS
Similar to Escherichia coli glycyl-tRNA synthetase beta chain GlyS or GlyS(B) or b3559 SWALL:SYGB_ECOLI (SWALL:P00961) (688 aa) fasta scores: E(): 1.6e-102, 44.5% id in 692 aa, and to Ralstonia solanacearum glycyl-tRNA synthetase beta chain glyS or rsc0524 or rs04944 SWALL:Q8Y213 (EMBL:AL646059) (697 aa) fasta scores: E(): 1.2e-166, 64.56% id in 697 aa, and to Neisseria meningitidis glycyl-tRNA synthetase beta chain glyS or nma0523 SWALL:Q9JW67 (EMBL:AL162753) (687 aa) fasta scores: E(): 2.9e-123, 51.36% id in 695 aa.
  
    0.755
BPSS0425
Putative heptosyltransferase (O-antigen related); Similar to Escherichia coli lipopolysaccharide heptosyltransferase-1 RfaC or WaaC or Rfa-2 or b3621 SWALL:RFAC_ECOLI (SWALL:P24173) (319 aa) fasta scores: E(): 7.8e-07, 26.45% id in 310 aa, and to Rhizobium loti ADP-heptose-LPS heptosyltransferase mlr2566 SWALL:Q98I51 (EMBL:AP003000) (335 aa) fasta scores: E(): 1.8e-15, 26.87% id in 346 aa.
 
   
 0.749
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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