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glpD glpD glpK glpK glpF glpF gpsA gpsA plsY plsY BPSL1613 BPSL1613 BPSS0260 BPSS0260 BPSS0261 BPSS0261 BPSL0665 BPSL0665 plsC plsC BPSL1189 BPSL1189
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpDSimilar to Pseudomonas aeruginosa glycerol-3-phosphate dehydrogenase GlpD or pa3584 SWALL:GLPD_PSEAE (SWALL:P52111) (512 aa) fasta scores: E(): 9.6e-105, 57.91% id in 480 aa, and to Xanthomonas axonopodis glycerol-3-phosphate dehydrogenase GlpD or xac0360 SWALL:AAM35252 (EMBL:AE011662) (501 aa) fasta scores: E(): 5.5e-117, 63.25% id in 479 aa, and to Xanthomonas campestris glycerol-3-phosphate dehydrogenase GlpD or xcc0360 SWALL:AAM39679 (EMBL:AE012132) (508 aa) fasta scores: E(): 5.5e-116, 61.38% id in 505 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (510 aa)    
Predicted Functional Partners:
glpK
Putative glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 0.999
glpF
Putative glycerol uptake facilitator protein; Similar to Thermus aquaticus glycerol facilitator glpF SWALL:Q93RA7 (EMBL:AB053202) (272 aa) fasta scores: E(): 7e-43, 50.64% id in 231 aa, and to Thermotoga maritima probable glycerol uptake facilitator protein GlpF or tm1429 SWALL:GLPF_THEMA (SWALL:Q9X1E3) (234 aa) fasta scores: E(): 1.1e-50, 56.83% id in 234 aa, and to Thermoanaerobacter tengcongensis glycerol uptake facilitator and related permeases GlpF or tte2003 SWALL:Q8R5R1 (EMBL:AE013151) (242 aa) fasta scores: E(): 2.3e-45, 52.11% id in 236 aa; Belongs to the MIP/aquaporin (TC 1.A [...]
 
  
 0.956
gpsA
Similar to Bacillus subtilis glycerol-3-phosphate dehydrogenase [NAD(P)+] GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 9.9e-39, 42.26% id in 336 aa, and to Ralstonia solanacearum glycerol-3-phosphate dehydrogenase [NAD(P)+] rsc0357 or rs03324 SWALL:GPDA_RALSO (SWALL:Q8Y2H9) (338 aa) fasta scores: E(): 1.2e-79, 68.24% id in 337 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 0.939
plsY
Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.922
BPSL1613
Putative glycerol utilisation-related protein; Similar to Agrobacterium tumefaciens 3,4-dihydroxy-2-butanone kinase atu3543 or agr_l_2580 SWALL:Q8UA32 (EMBL:AE009283) (564 aa) fasta scores: E(): 5.5e-112, 60.17% id in 570 aa, and to Lycopersicon esculentum putative 3,4-dihydroxy-2-butanone kinase DhbK SWALL:DHBK_LYCES (SWALL:O04059) (594 aa) fasta scores: E(): 4.6e-59, 43.42% id in 578 aa.
    
 0.860
BPSS0260
Putative kinase; Similar to Yersinia pestis putative dihydroxyacetone kinase DhaK or ypo3350 SWALL:Q8ZBQ7 (EMBL:AJ414156) (333 aa) fasta scores: E(): 2.1e-72, 62.72% id in 330 aa, and to Selenomonas ruminantium subsp. ruminantium dihydroxyacetone kinase DhaK1 SWALL:Q93PV9 (EMBL:AF297121) (329 aa) fasta scores: E(): 2.6e-45, 43.3% id in 321 aa.
    
 0.841
BPSS0261
Putative kinase; Similar to the plasmid-borne Rhizobium meliloti putative dihydroxyacetone kinase protein rb0299 or smb20313 SWALL:Q92WN3 (EMBL:AL603643) (213 aa) fasta scores: E(): 5.6e-36, 54.93% id in 213 aa, and to Selenomonas ruminantium subsp. ruminantium dihydroxyacetone kinase DhaK2 SWALL:Q9F677 (EMBL:AF297121) (207 aa) fasta scores: E(): 1.2e-19, 37.18% id in 199 aa.
    
 0.841
BPSL0665
Similar to Ralstonia solanacearum putative acyltransferase transmembrane protein rsc0522 or rs04959 SWALL:Q8Y215 (EMBL:AL646059) (250 aa) fasta scores: E(): 9.8e-67, 65.59% id in 250 aa, and to Pseudomonas aeruginosa probable acyltransferase pa0005 SWALL:Q9I7C1 (EMBL:AE004440) (257 aa) fasta scores: E(): 6.3e-40, 43.8% id in 242 aa, and to Pseudomonas fluorescens putative N-acylhomoserine lactone synthase HdtS SWALL:Q9F728 (EMBL:AF286536) (259 aa) fasta scores: E(): 3.2e-37, 40.58% id in 239 aa.
    
 0.836
plsC
Previously sequenced as Burkholderia pseudomallei putative 1-acyl-SN-glycerol-3-phosphate acyltransferase PlsC SWALL:O69114 (EMBL:AF064070) (289 aa) fasta scores: E(): 1.5e-111, 100% id in 289 aa. Also highly similar to Neisseria meningitidis 1-acyl-SN-glycerol-3-phosphate acyltransferase Plsc or nmb1294 SWALL:PLSC_NEIMB (SWALL:Q9JZ47) (255 aa) fasta scores: E(): 3.4e-18, 33.88% id in 242 aa.
    
 0.836
BPSL1189
Putative kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
    
  0.804
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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