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BPSL0732 BPSL0732 BPSL2025 BPSL2025 BPSS2246 BPSS2246 BPSS1940 BPSS1940 BPSL0734 BPSL0734 BPSS1495 BPSS1495 BPSS2345 BPSS2345 BPSS1360 BPSS1360 BPSS1876 BPSS1876 BPSL2299 BPSL2299 BPSL0703 BPSL0703
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSL0732Putative two-component regulator histidine sensor kinase; Similar to Rhodobacter sphaeroides DMSO/TMAO-sensor kinase dorS SWALL:O30740 (EMBL:AF016236) (815 aa) fasta scores: E(): 4.6e-25, 33.24% id in 385 aa, and to Caulobacter crescentus sensor histidine kinase / response regulator cc0723 SWALL:Q9AA83 (EMBL:AE005747) (591 aa) fasta scores: E(): 1.6e-27, 30.34% id in 412 aa, and to Xanthomonas campestris two-component system sensor protein xcc2360 SWALL:AAM41638 (EMBL:AE012344) (1364 aa) fasta scores: E(): 3.7e-26, 29.7% id in 404 aa. (602 aa)    
Predicted Functional Partners:
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
 
 
0.992
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
 
 
0.992
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
 
0.991
BPSL0734
Putative two-component transcriptional response regulator; From codon 189-321 similar to Xanthomonas axonopodis two-component system regulatory protein colR or xac1221 SWALL:AAM36093 (EMBL:AE011752) (238 aa) fasta scores: E(): 0.0042, 24.21% id in 128 aa, and to Ralstonia solanacearum probable two-component system response regulator transcription regulator protein rsc1073 or rs04004 SWALL:Q8Y0H1 (EMBL:AL646062) (237 aa) fasta scores: E(): 0.0087, 30.46% id in 128 aa.
 
   0.943
BPSS1495
Putative two-component regulator sensor kinase; Similar to Pseudomonas aeruginosa probable two-component sensor pa2571 SWALL:Q9I0R5 (EMBL:AE004685) (470 aa) fasta scores: E(): 4.9e-11, 26.43% id in 401 aa, and to Chlorobium tepidum sensor histidine kinase/response regulator ct1396 SWALL:AAM72624 (EMBL:AE012897) (808 aa) fasta scores: E(): 2.1e-06, 29.09% id in 409 aa, and to Anabaena sp. two-component hybrid sensor and regulator alr1968 SWALL:Q8YVK7 (EMBL:AP003587) (759 aa) fasta scores: E(): 2.3e-06, 29.8% id in 312 aa.
 
 
0.917
BPSS2345
Sensory kinase protein; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Brucella melitensis sensory transduction protein kinase bmei0947 SWALL:Q8YH57 (EMBL:AE009535) (767 aa) fasta scores: E(): 1.7e-39, 35.64% id in 418 aa, and Caulobacter crescentus sensory box histidine kinase/response regulator cc2874 SWALL:Q9A4G0 (EMBL:AE005952) (794 aa) fasta scores: E(): 1.6e-34, 33.82% id in 541 aa. Possible alternative translational start site.
 
0.910
BPSS1360
Putative two-component sensor kinase protein; C-terminus is similar to the C-terminal regions of Anabaena sp. cyanobacterial phytochrome A AphA or ALR3157 SWALL:PHYA_ANASP (SWALL:Q9LCC2) (765 aa) fasta scores: E(): 3.5e-45, 54.78% id in 261 aa, and to Methanosarcina acetivorans sensory transduction histidine kinase MA1270 SWALL:Q8TRB0 (EMBL:AE010795) (1456 aa) fasta scores: E(): 4.8e-62, 41.14% id in 508 aa.
 
0.908
BPSS1876
Putative sensor kinase/response regulator fusion protein; N-terminal region similar to Pseudomonas aeruginosa probable two-component response regulator pa3702 SWALL:Q9HXT9 (EMBL:AE004789) (347 aa) fasta scores: E(): 3.7e-29, 64.92% id in 134 aa, C-terminal region to Caulobacter crescentus sensory box histidine kinase, putative cc3327 SWALL:Q9A377 (EMBL:AE005994) (761 aa) fasta scores: E(): 9.5e-22, 37.61% id in 226 aa, and in full length to Mycobacterium leprae sensor-like histidine kinase SenX3 or ml2440 or b2168_c3_247 SWALL:SEX3_MYCLE (SWALL:P54883) (443 aa) fasta scores: E(): 1.9e- [...]
 
0.904
BPSL2299
Putative dihydrolipoamide dehydrogenase; C-terminal region is similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 dihydrolipoamide dehydrogenase LpdA or Lpd SWALL:DLDH_ECOLI (SWALL:P00391) (473 aa) fasta scores: E(): 1.9e-93, 65.75% id in 473 aa. Full length CDS is similar to Ralstonia solanacearum probable dihydrolipoamide dehydrogenase rsc1603 or rs03965 SWALL:Q8XZ03 (EMBL:AL646065) (594 aa) fasta scores: E(): 2.1e-142, 76.88% id in 597 aa.
    
 0.882
BPSL0703
Putative two-component sensor histidine kinase; Similar to Xanthomonas campestris histidine kinase xcc1957 SWALL:AAM41246 (EMBL:AE012299) (408 aa) fasta scores: E(): 1.1e-42, 50.16% id in 297 aa, and to Xanthomonas axonopodis histidine kinase xac1991 SWALL:AAM36853 (EMBL:AE011834) (408 aa) fasta scores: E(): 1.3e-42, 49.49% id in 297 aa, and to Pseudomonas aeruginosa probable two-component sensor pa2571 SWALL:Q9I0R5 (EMBL:AE004685) (470 aa) fasta scores: E(): 1.4e-42, 46.93% id in 326 aa.
 
0.875
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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