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sucC sucC sucD sucD BPSS1720 BPSS1720 BPSS1719 BPSS1719 sucA sucA sdhA sdhA sucB sucB sdhB sdhB sdhB-2 sdhB-2 BPSL2299 BPSL2299 pdhB pdhB
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
sucCsuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA ligase alpha-chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
BPSS1720
Similar to Ralstonia solanacearum putative transmembrane succinate dehydrogenase SdhC or rsc1996 or rs03564 SWALL:Q8XXW7 (EMBL:AL646067) (140 aa) fasta scores: E(): 1.1e-30, 58.69% id in 138 aa, and to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 7.3e-11, 35.15% id in 128 aa.
  
 
 0.991
BPSS1719
Putative succinate dehydrogenase; Similar to Ralstonia solanacearum putative transmembrane succinate dehydrogenase sdhd or rsc1995 or rs03563 SWALL:Q8XXW8 (EMBL:AL646067) (121 aa) fasta scores: E(): 1.2e-35, 71.31% id in 122 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri succinate dehydrogenase hydrophobic membrane anchor protein sdhd or b0722 or c0800 or sf0575 SWALL:DHSD_ECOLI (SWALL:P10445) (115 aa) fasta scores: E(): 1.7e-10, 32.69% id in 104 aa.
  
 
 0.990
sucA
2-oxoglutarate dehydrogenase E1 component; Similar to Escherichia coli, and Escherichia coli O157:H7 2-oxoglutarate dehydrogenase E1 component SucA or b0726 or z0880 or ecs0751 SWALL:ODO1_ECOLI (SWALL:P07015) (933 aa) fasta scores: E(): 1.8e-205, 55.07% id in 946 aa, and to Alcaligenes eutrophus 2-oxoglutarate dehydrogenase E1 component OdhA SWALL:ODO1_ALCEU (SWALL:Q59106) (950 aa) fasta scores: E(): 0, 77.39% id in 951 aa.
 
 0.987
sdhA
Succinate dehydrogenase flavoprotein subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 succinate dehydrogenase flavoprotein subunit SdhA or b0723 or c0801 or z0877 or ecs0748 SWALL:DHSA_ECOLI (SWALL:P10444) (588 aa) fasta scores: E(): 7.9e-127, 55.46% id in 586 aa, and to Ralstonia solanacearum putative succinate dehydrogenase SdhA or rsc1994 or rs03562 SWALL:Q8XXW9 (EMBL:AL646067) (592 aa) fasta scores: E(): 6.1e-201, 85.3% id in 592 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
 0.987
sucB
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.980
sdhB
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or b0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 5.9e-65, 66.81% id in 232 aa, and to Ralstonia solanacearum putative succinate dehydrogenase rsc1993 or rs03561 SWALL:Q8XXX0 (EMBL:AL646067) (233 aa) fasta scores: E(): 5.5e-89, 90.51% id in 232 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.980
sdhB-2
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 3.3e-63, 63.79% id in 232 aa, and to Ralstonia solanacearum putative succinate dehydrogenase rsc1993 or rs03561 SWALL:Q8XXX0 (EMBL:AL646067) (233 aa) fasta scores: E(): 1.7e-74, 73.16% id in 231 aa. Similar to BPSS1717, 74.459% identity (74.783% ungapped) in 231 aa overlap.
 
 0.980
BPSL2299
Putative dihydrolipoamide dehydrogenase; C-terminal region is similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 dihydrolipoamide dehydrogenase LpdA or Lpd SWALL:DLDH_ECOLI (SWALL:P00391) (473 aa) fasta scores: E(): 1.9e-93, 65.75% id in 473 aa. Full length CDS is similar to Ralstonia solanacearum probable dihydrolipoamide dehydrogenase rsc1603 or rs03965 SWALL:Q8XZ03 (EMBL:AL646065) (594 aa) fasta scores: E(): 2.1e-142, 76.88% id in 597 aa.
  
 0.965
pdhB
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.942
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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