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purC purC purE purE purD purD purK purK purB purB purL purL purH purH purF purF purM purM purN purN BPSS1693 BPSS1693
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
purCSimilar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. (296 aa)    
Predicted Functional Partners:
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.998
purD
Similar to Escherichia coli phosphoribosylamine--glycine ligase PurD or b4005 SWALL:PUR2_ECOLI (SWALL:P15640) (429 aa) fasta scores: E(): 1.5e-94, 60.42% id in 427 aa, and to Ralstonia solanacearum phosphoribosylamine--glycine ligase rsc2191 or rs01408 SWALL:PUR2_RALSO (SWALL:Q8XXC4) (422 aa) fasta scores: E(): 3.5e-122, 74.88% id in 422 aa; Belongs to the GARS family.
 
 0.992
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
 
 0.986
purB
Adenylosuccinate lyase; Similar to Escherichia coli, and Escherichia coli O6 adenylosuccinate lyase PurB or b1131 or c1510 SWALL:PUR8_ECOLI (SWALL:P25739) (456 aa) fasta scores: E(): 2.5e-109, 62.55% id in 454 aa, and to Ralstonia solanacearum probable adenylosuccinate lyase protein rsc2720 or rs00002 SWALL:Q8XVV7 (EMBL:AL646071) (457 aa) fasta scores: E(): 9.1e-148, 82.41% id in 455 aa. Note: This CDS is longer in its N-terminal region than most of its database matches. It contains an alternative start codon at residue 22.
  
 0.986
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
 
 0.982
purH
Similar to Escherichia coli bifunctional purine biosynthesis protein [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (aicar transformylase); IMP cyclohydrolase (EC 3.5.4.10) (inosinicase) (IMP synthetase) (atic)] PurH or b4006 SWALL:PUR9_ECOLI (SWALL:P15639) (529 aa) fasta scores: E(): 1.5e-122, 62.28% id in 525 aa, and to Ralstonia solanacearum probable bifunctional: phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase transmembrane protein rsc0504 or rs05018 SWALL:Q8Y232 (EMBL:AL646059) (524 aa) fasta scores: E(): 4.6e-170 [...]
  
 
 0.966
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.965
purM
Similar to Escherichia coli phosphoribosylformylglycinamidine cyclo-ligase PurM or PurG or b2499 SWALL:PUR5_ECOLI (SWALL:P08178) (344 aa) fasta scores: E(): 2.9e-78, 59.76% id in 343 aa, and to Ralstonia solanacearum probable phosphoribosylformylglycinamidine cyclo-ligase PurM or rsc2623 or rs00927 SWALL:Q8XW52 (EMBL:AL646071) (353 aa) fasta scores: E(): 1.9e-108, 81.21% id in 346 aa, and to Neisseria meningitidis putative phosphoribosylformylglycinamidine cyclo-ligase PurM or nma1421 SWALL:Q9JUA2 (EMBL:AL162755) (344 aa) fasta scores: E(): 7.4e-90, 68.73% id in 339 aa.
  
  
 0.951
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.882
BPSS1693
Putative bacteriocin production related protein; Similar to Ralstonia solanacearum probable colicin V production transmembrane protein CvpA or rsc1977 or rs03551 SWALL:Q8XXY6 (EMBL:AL646067) (165 aa) fasta scores: E(): 1.7e-23, 45.34% id in 161 aa, and to Escherichia coli colicin V production protein CvpA or DedE or b2313 SWALL:CVPA_ECOLI (SWALL:P08550) (162 aa) fasta scores: E(): 1.4e-08, 35% id in 140 aa.
  
    0.876
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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