node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPSL0750 | BPSL0802 | BPSL0750 | BPSL0802 | Hypothetical protein; C-terminal region is similar to Escherichia coli O157:H7 hypothetical protein z0331 or ecs0295 SWALL:Q8X7J2 (EMBL:AE005203) (188 aa) fasta scores: E(): 4.3e-09, 27.52% id in 178 aa. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.412 |
BPSL0802 | BPSL0750 | BPSL0802 | BPSL0750 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Hypothetical protein; C-terminal region is similar to Escherichia coli O157:H7 hypothetical protein z0331 or ecs0295 SWALL:Q8X7J2 (EMBL:AE005203) (188 aa) fasta scores: E(): 4.3e-09, 27.52% id in 178 aa. | 0.412 |
BPSL0802 | BPSL1499 | BPSL0802 | BPSL1499 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.413 |
BPSL0802 | glyA | BPSL0802 | BPSL2758 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.459 |
BPSL0802 | glyA-2 | BPSL0802 | BPSS0547 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.425 |
BPSL0802 | hemK | BPSL0802 | BPSL3074 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Protein methyltransferase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.669 |
BPSL0802 | purC | BPSL0802 | BPSL0799 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. | 0.555 |
BPSL0802 | purE | BPSL0802 | BPSL0800 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.606 |
BPSL0802 | purK | BPSL0802 | BPSL0801 | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.821 |
BPSL1499 | BPSL0802 | BPSL1499 | BPSL0802 | Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.413 |
glyA | BPSL0802 | BPSL2758 | BPSL0802 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.459 |
glyA | glyA-2 | BPSL2758 | BPSS0547 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.903 |
glyA | purC | BPSL2758 | BPSL0799 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. | 0.708 |
glyA-2 | BPSL0802 | BPSS0547 | BPSL0802 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.425 |
glyA-2 | glyA | BPSS0547 | BPSL2758 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.903 |
glyA-2 | purC | BPSS0547 | BPSL0799 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. | 0.708 |
hemK | BPSL0802 | BPSL3074 | BPSL0802 | Protein methyltransferase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.669 |
purC | BPSL0802 | BPSL0799 | BPSL0802 | Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.555 |
purC | glyA | BPSL0799 | BPSL2758 | Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.708 |
purC | glyA-2 | BPSL0799 | BPSS0547 | Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.708 |