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BPSL0802 BPSL0802 purK purK hemK hemK purE purE purC purC glyA glyA glyA-2 glyA-2 BPSL1499 BPSL1499 BPSL0750 BPSL0750
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Predicted Interactions
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BPSL0802Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (341 aa)    
Predicted Functional Partners:
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
     0.821
hemK
Protein methyltransferase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
  
 0.669
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.606
purC
Similar to Corynebacterium ammoniagenes 5'-phosphoribosyl-4-N-succinocarboxamide-5-amino imidazole synthetase PurC SWALL:Q9RHX2 (EMBL:AB003161) (295 aa) fasta scores: E(): 2.6e-53, 52.66% id in 281 aa, and to Ralstonia solanacearum phosphoribosylaminoimidazole-succinocarboxamide synthase rsc0574 or rs04891 SWALL:Q8Y1W3 (EMBL:AL646060) (302 aa) fasta scores: E(): 9.8e-93, 76.92% id in 299 aa.
  
  
 0.555
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.459
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.425
BPSL1499
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
 
     0.413
BPSL0750
Hypothetical protein; C-terminal region is similar to Escherichia coli O157:H7 hypothetical protein z0331 or ecs0295 SWALL:Q8X7J2 (EMBL:AE005203) (188 aa) fasta scores: E(): 4.3e-09, 27.52% id in 178 aa.
   
   0.412
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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