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dfp dfp dut dut coaD coaD coaX coaX panC panC BPSL1542 BPSL1542 RibC RibC BPSL1716 BPSL1716 lspA lspA priA priA tmk tmk
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second shell of interactors
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Predicted Interactions
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textmining
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dfpPutative DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
  
 0.947
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.945
coaX
Bordetella pertussis Bvg accessory factor family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.935
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.900
BPSL1542
Similar to Escherichia coli cystathionine beta-lyase MetC or b3008 SWALL:METC_ECOLI (SWALL:P06721) (395 aa) fasta scores: E(): 5.8e-47, 37.84% id in 362 aa, and to Ralstonia solanacearum putative cystathionine beta-lyase rsc1639 or rs04013 SWALL:Q8XYW7 (EMBL:AL646065) (404 aa) fasta scores: E(): 3.2e-94, 64.43% id in 388 aa.
  
 
  0.828
RibC
Similar to Pseudomonas fluorescens riboflavin biosynthesis protein RibF [includes: riboflavin kinase; FMN adenylyltransferase] RibF SWALL:RIBF_PSEFL (SWALL:P22990) (311 aa) fasta scores: E(): 4.2e-48, 49.35% id in 310 aa, and to Ralstonia solanacearum probable riboflavin biosynthesis protein RibF or rsc2457 or rs01148 SWALL:Q8XWL7 (EMBL:AL646070) (332 aa) fasta scores: E(): 1.1e-88, 70.87% id in 333 aa, and to Pseudomonas aeruginosa riboflavin kinase/fad synthase ribF or pa4561 SWALL:Q9HVM3 (EMBL:AE004869) (312 aa) fasta scores: E(): 7.8e-49, 49.03% id in 310 aa.
 
   
 0.824
BPSL1716
Similar to Rhizobium loti cysteine synthase mll9227 SWALL:Q981U9 (EMBL:AP003015) (351 aa) fasta scores: E(): 4.2e-53, 45.74% id in 341 aa, and to Alcaligenes eutrophus cysteine synthase CysM SWALL:CYSM_ALCEU (SWALL:Q44004) (339 aa) fasta scores: E(): 9.2e-16, 31.35% id in 303 aa.
    
  0.814
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
    0.734
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
    0.717
tmk
Putative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.649
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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