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cysI cysI cysH cysH BPSS1241 BPSS1241 BPSS1464 BPSS1464 cysC-2 cysC-2 BPSL0957 BPSL0957 BPSL1716 BPSL1716 metZ metZ BPSS1766 BPSS1766 BPSL1560 BPSL1560 BPSS2301 BPSS2301
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
cysISimilar to Pseudomonas aeruginosa sulfite reductase CysI SWALL:O31037 (EMBL:AF026066) (552 aa) fasta scores: E(): 9.2e-145, 64.91% id in 553 aa, and to Ralstonia solanacearum probable sulfite reductase oxidoreductase protein CysI1 or rsc2425 or rs02684 SWALL:Q8XWP8 (EMBL:AL646070) (553 aa) fasta scores: E(): 3.4e-169, 73.65% id in 558 aa, and to Pseudomonas aeruginosa sulfite reductase CysI or pa1838 SWALL:Q9I2Q7 (EMBL:AE004609) (552 aa) fasta scores: E(): 9.9e-152, 67.26% id in 553 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (559 aa)    
Predicted Functional Partners:
cysH
Putative phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
 0.998
BPSS1241
Putative bifunctional reductase; Possible fusion protein. N-terminal region is similar to Synechococcus sp. nitrate reductase NarB SWALL:NARB_SYNP7 (SWALL:P39458) (729 aa) fasta scores: E(): 9.4e-73, 43.09% id in 724 aa. C-terminal region is similar to Escherichia coli sulfite reductase [NADPH] flavoprotein alpha-component CysJ SWALL:CYSJ_ECOLI (SWALL:P38038) (598 aa) fasta scores: E(): 8.1e-70, 39.13% id in 598 aa; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 0.983
BPSS1464
Putative transmembrane NADPH flavoprotein; Similar to Brucella melitensis sulfite reductase bmeii1011 SWALL:Q8YB89 (EMBL:AE009733) (733 aa) fasta scores: E(): 3.7e-34, 44.75% id in 782 aa, and to Caulobacter crescentus sulfite reductase cc3063 SWALL:Q9A3Y7 (EMBL:AE005969) (504 aa) fasta scores: E(): 9.1e-17, 31.37% id in 510 aa.
  
 0.981
cysC-2
Putative adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.970
BPSL0957
Similar to Ralstonia solanacearum hypothetical protein rsc2424 or rs02687 SWALL:Q8XWP9 (EMBL:AL646070) (194 aa) fasta scores: E(): 1.3e-33, 57.39% id in 169 aa, and to Pseudomonas aeruginosa hypothetical protein Pa1837 pa1837 SWALL:Q9I2Q8 (EMBL:AE004609) (165 aa) fasta scores: E(): 9.1e-32, 55.23% id in 172 aa.
 
  
 0.967
BPSL1716
Similar to Rhizobium loti cysteine synthase mll9227 SWALL:Q981U9 (EMBL:AP003015) (351 aa) fasta scores: E(): 4.2e-53, 45.74% id in 341 aa, and to Alcaligenes eutrophus cysteine synthase CysM SWALL:CYSM_ALCEU (SWALL:Q44004) (339 aa) fasta scores: E(): 9.2e-16, 31.35% id in 303 aa.
  
 
 0.939
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.934
BPSS1766
Putative sulfurtransferase (cyanide detoxification); Similar to Escherichia coli 3-mercaptopyruvate sulfurtransferase SseA or b2521 SWALL:THTM_ECOLI (SWALL:P31142) (280 aa) fasta scores: E(): 3.6e-21, 33.09% id in 284 aa, and to Pseudomonas aeruginosa probable 3-mercaptopyruvate sulfurtransferase pa1292 SWALL:THTM_PSEAE (SWALL:Q9I452) (284 aa) fasta scores: E(): 1.5e-49, 50.17% id in 281 aa.
    
 0.921
BPSL1560
Hypothetical protein; C-terminal region similar to Pseudomonas aeruginosa hypothetical protein pa2345 SWALL:Q9I1D3 (EMBL:AE004660) (411 aa) fasta scores: E(): 2.1e-93, 59.66% id in 414 aa, and N-terminal region to Rhodobacter capsulatus hypothetical protein SWALL:O33514 (EMBL:U23145) (146 aa) fasta scores: E(): 1.6e-13, 42.17% id in 147 aa. Posible fusion protein.
   
 0.910
BPSS2301
Putative membrane protein; Similar to Rhizobium loti DMSO reductase chain C mll5612 SWALL:Q98BE5 (EMBL:AP003007) (311 aa) fasta scores: E(): 5.9e-26, 36.42% id in 324 aa. N-terminus is weakly similar to the N-terminal region of Escherichia coli anaerobic dimethyl sulfoxide reductase chain C DmsC SWALL:DMSC_ECOLI (SWALL:P18777) (287 aa) fasta scores: E(): 0.03, 27.67% id in 224 aa.
    
 0.910
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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