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BPSL1057 BPSL1057 BPSS2216 BPSS2216 BPSS0822 BPSS0822 BPSS2104 BPSS2104 BPSL1628 BPSL1628 BPSS1268 BPSS1268 pilR pilR BPSS1622 BPSS1622 BPSS0796 BPSS0796 glyA-2 glyA-2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
BPSL1057Putative membrane protein (fragment); 2 probable transmembrane helices predicted for BPSL1056 by TMHMM2.0 at aa 19-41 and 51-73. (158 aa)    
Predicted Functional Partners:
BPSS2216
Putative membrane protein; Similar to Ralstonia solanacearum probable transmembrane protein RS02225 SWALL:Q8XPH4 (EMBL:AL646086) (72 aa) fasta scores: E(): 2.1e-11, 74.13% id in 58 aa, and to Bordetella pertussis putative membrane protein SWALL:Q7VXL6 (EMBL:BX640416) (53 aa) fasta scores: E(): 4.3e-10, 69.81% id in 53 aa. Possible alternative translational start site after codon 16.
  
  
 0.518
BPSS0822
Hypothetical protein; Poor database matches. Weakly similar to an internal region of Streptomyces coelicolor hypothetical protein SCO6522 or SC5C7.07 SWALL:O86704 (EMBL:AL939128) (480 aa) fasta scores: E(): 0.13, 29.41% id in 306 aa.
      
 0.497
BPSS2104
Putative membrane protein; Similar to Vibrio cholerae IcmF-related protein vca0120 or IcmF SWALL:Q9KN45 (EMBL:AE004353) (1181 aa) fasta scores: E(): 6.1e-46, 26.92% id in 1237 aa, and to Rhizobium loti hypothetical protein Mlr2360 SWALL:Q98IK4 (EMBL:AP002999) (1176 aa) fasta scores: E(): 3e-103, 33.08% id in 1209 aa, and to Xanthomonas axonopodis hypothetical protein Xac4119 SWALL:AAM38954 (EMBL:AE012061) (1176 aa) fasta scores: E(): 2.2e-77, 34.27% id in 1205 aa.
      
 0.495
BPSL1628
Similar to Salmonella typhimurium putative fimbrial usher StiC or stm0175 SWALL:Q8ZRR6 (EMBL:AE008702) (848 aa) fasta scores: E(): 1.6e-89, 34.28% id in 872 aa, and to Escherichia coli outer membrane usher protein AfaC precursor SWALL:AFAC_ECOLI (SWALL:P53517) (859 aa) fasta scores: E(): 9.4e-79, 32% id in 881 aa.
      
 0.408
BPSS1268
Putative efflux system protein; Similar to Escherichia coli tetracycline resistance protein, class A TetA SWALL:TCR1_ECOLI (SWALL:P02982) (399 aa) fasta scores: E(): 4.6e-38, 35.75% id in 400 aa, and to Xanthomonas axonopodis tetracycline-efflux transporter TetA or xac4295 SWALL:AAM39125 (EMBL:AE012083) (421 aa) fasta scores: E(): 3.8e-46, 40.75% id in 400 aa, and to Xanthomonas campestris tetracycline-efflux transporter TetA or xcc4156 SWALL:AAM43372 (EMBL:AE012541) (420 aa) fasta scores: E(): 5.9e-43, 36.85% id in 407 aa.
      
 0.406
pilR
Putative type IV pilus biosynthesis protein; Similar to Escherichia coli BfpE SWALL:Q47071 (EMBL:Z68186) (352 aa) fasta scores: E(): 3e-47, 38.06% id in 352 aa, and to Salmonella typhi, and Salmonella dublin PilR or sty4546 SWALL:Q9ZIV0 (EMBL:AF000001) (361 aa) fasta scores: E(): 9.3e-29, 34.07% id in 361 aa.
      
 0.406
BPSS1622
Putative type III secretion protein; Similar to Burkholderia pseudomallei hypothetical 19.6 kDa protein SWALL:Q93KZ3 (EMBL:AF074878) (178 aa) fasta scores: E(): 2.1e-14, 35.29% id in 170 aa, and to Xanthomonas oryzae HrpBL SWALL:Q9K2Q2 (EMBL:AB045311) (151 aa) fasta scores: E(): 4.2e-05, 31.7% id in 123 aa.
      
 0.406
BPSS0796
Putative surface-exposed protein; Similar to many low complexity proteins, including Rhizobium loti hypothetical glycine-rich protein mlr0587 SWALL:Q98MG7 (EMBL:AP002995) (3145 aa) fasta scores: E(): 1.3e-32, 24.78% id in 1743 aa. Possible alternative translational start site. Similar to BPSL1705, 65.523% identity (70.872% ungapped) in 1749 aa overlap.
      
 0.405
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      
 0.402
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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