htpG protein (Burkholderia pseudomallei) - STRING interaction network

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Score

htpG

Chaperone protein; Molecular chaperone. Has ATPase activity. (632 aa)

Predicted Functional Partners:

dnaJ

0.996

dnaK

0.973

hscA

0.961

BPSS1095

0.961

BPSS1096

0.961

BPSL3080

0.960

fbp-2

0.944

BPSL1666

0.932

groL

0.930

ppiA

0.928

Your Current Organism:

Burkholderia pseudomallei

NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPSL1666	BPSL3080	BPSL1666	BPSL3080	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Putative chaperone protein; Similar to Rhizobium loti DnaK-type molecular chaperone, DnaK Mll5617 SWALL:Q98BE0 (EMBL:AP003007) (418 aa) fasta scores: E(): 1e-61, 44.89% id in 421 aa, and to Chlamydia muridarum chaperone protein DnaK or Tc0675 SWALL:DNAK_CHLMU (SWALL:P56836) (654 aa) fasta scores: E(): 1.7e-05, 26.8% id in 250 aa, and to Vibrio cholerae chaperone protein DnaK or Vc0855 SWALL:DNAK_VIBCH (SWALL:O34241) (635 aa) fasta scores: E(): 2e-05, 26.12% id in 421 aa.	0.673
BPSL1666	BPSS1095	BPSL1666	BPSS1095	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	0.615
BPSL1666	BPSS1096	BPSL1666	BPSS1096	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Similar to Legionella pneumophila chaperone protein DnaK to codon 347 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 3e-06, 25.72% id in 346 aa, and to the full-length Vibrio cholerae DnaK-related protein vc1373 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 1.3e-84, 47.05% id in 952 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 606 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 1.6e-46, 40.6% id in 628 aa.	0.615
BPSL1666	dnaJ	BPSL1666	BPSL2826	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Putative DnaJ chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	0.876
BPSL1666	dnaK	BPSL1666	BPSL2827	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Putative DnaK chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.615
BPSL1666	hscA	BPSL1666	BPSL2285	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.	0.615
BPSL1666	htpG	BPSL1666	BPSL1087	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Chaperone protein; Molecular chaperone. Has ATPase activity.	0.932
BPSL1666	ppiA	BPSL1666	BPSL2245	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	Peptidyl-prolyl cis-trans isomerase A precursor; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.810
BPSL3080	BPSL1666	BPSL3080	BPSL1666	Putative chaperone protein; Similar to Rhizobium loti DnaK-type molecular chaperone, DnaK Mll5617 SWALL:Q98BE0 (EMBL:AP003007) (418 aa) fasta scores: E(): 1e-61, 44.89% id in 421 aa, and to Chlamydia muridarum chaperone protein DnaK or Tc0675 SWALL:DNAK_CHLMU (SWALL:P56836) (654 aa) fasta scores: E(): 1.7e-05, 26.8% id in 250 aa, and to Vibrio cholerae chaperone protein DnaK or Vc0855 SWALL:DNAK_VIBCH (SWALL:O34241) (635 aa) fasta scores: E(): 2e-05, 26.12% id in 421 aa.	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	0.673
BPSL3080	dnaJ	BPSL3080	BPSL2826	Putative chaperone protein; Similar to Rhizobium loti DnaK-type molecular chaperone, DnaK Mll5617 SWALL:Q98BE0 (EMBL:AP003007) (418 aa) fasta scores: E(): 1e-61, 44.89% id in 421 aa, and to Chlamydia muridarum chaperone protein DnaK or Tc0675 SWALL:DNAK_CHLMU (SWALL:P56836) (654 aa) fasta scores: E(): 1.7e-05, 26.8% id in 250 aa, and to Vibrio cholerae chaperone protein DnaK or Vc0855 SWALL:DNAK_VIBCH (SWALL:O34241) (635 aa) fasta scores: E(): 2e-05, 26.12% id in 421 aa.	Putative DnaJ chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	0.969
BPSL3080	fbp-2	BPSL3080	BPSS1823	Putative chaperone protein; Similar to Rhizobium loti DnaK-type molecular chaperone, DnaK Mll5617 SWALL:Q98BE0 (EMBL:AP003007) (418 aa) fasta scores: E(): 1e-61, 44.89% id in 421 aa, and to Chlamydia muridarum chaperone protein DnaK or Tc0675 SWALL:DNAK_CHLMU (SWALL:P56836) (654 aa) fasta scores: E(): 1.7e-05, 26.8% id in 250 aa, and to Vibrio cholerae chaperone protein DnaK or Vc0855 SWALL:DNAK_VIBCH (SWALL:O34241) (635 aa) fasta scores: E(): 2e-05, 26.12% id in 421 aa.	Similar to Neisseria meningitidis peptidyl-prolyl cis-trans isomerase Fbp or nmb0027 SWALL:FKBP_NEIMB (SWALL:P25138) (109 aa) fasta scores: E(): 2.6e-24, 66.66% id in 105 aa, and to Neurospora crassa FK506-binding protein 9g6.180 SWALL:FKBP_NEUCR (SWALL:P20080) (120 aa) fasta scores: E(): 1.3e-19, 53.5% id in 114 aa.	0.644
BPSL3080	groL	BPSL3080	BPSS0477	Putative chaperone protein; Similar to Rhizobium loti DnaK-type molecular chaperone, DnaK Mll5617 SWALL:Q98BE0 (EMBL:AP003007) (418 aa) fasta scores: E(): 1e-61, 44.89% id in 421 aa, and to Chlamydia muridarum chaperone protein DnaK or Tc0675 SWALL:DNAK_CHLMU (SWALL:P56836) (654 aa) fasta scores: E(): 1.7e-05, 26.8% id in 250 aa, and to Vibrio cholerae chaperone protein DnaK or Vc0855 SWALL:DNAK_VIBCH (SWALL:O34241) (635 aa) fasta scores: E(): 2e-05, 26.12% id in 421 aa.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.729
BPSL3080	htpG	BPSL3080	BPSL1087	Putative chaperone protein; Similar to Rhizobium loti DnaK-type molecular chaperone, DnaK Mll5617 SWALL:Q98BE0 (EMBL:AP003007) (418 aa) fasta scores: E(): 1e-61, 44.89% id in 421 aa, and to Chlamydia muridarum chaperone protein DnaK or Tc0675 SWALL:DNAK_CHLMU (SWALL:P56836) (654 aa) fasta scores: E(): 1.7e-05, 26.8% id in 250 aa, and to Vibrio cholerae chaperone protein DnaK or Vc0855 SWALL:DNAK_VIBCH (SWALL:O34241) (635 aa) fasta scores: E(): 2e-05, 26.12% id in 421 aa.	Chaperone protein; Molecular chaperone. Has ATPase activity.	0.960
BPSS1095	BPSL1666	BPSS1095	BPSL1666	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	0.615
BPSS1095	BPSS1096	BPSS1095	BPSS1096	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	Similar to Legionella pneumophila chaperone protein DnaK to codon 347 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 3e-06, 25.72% id in 346 aa, and to the full-length Vibrio cholerae DnaK-related protein vc1373 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 1.3e-84, 47.05% id in 952 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 606 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 1.6e-46, 40.6% id in 628 aa.	0.829
BPSS1095	dnaJ	BPSS1095	BPSL2826	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	Putative DnaJ chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]	0.963
BPSS1095	fbp-2	BPSS1095	BPSS1823	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	Similar to Neisseria meningitidis peptidyl-prolyl cis-trans isomerase Fbp or nmb0027 SWALL:FKBP_NEIMB (SWALL:P25138) (109 aa) fasta scores: E(): 2.6e-24, 66.66% id in 105 aa, and to Neurospora crassa FK506-binding protein 9g6.180 SWALL:FKBP_NEUCR (SWALL:P20080) (120 aa) fasta scores: E(): 1.3e-19, 53.5% id in 114 aa.	0.644
BPSS1095	groL	BPSS1095	BPSS0477	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.770
BPSS1095	htpG	BPSS1095	BPSL1087	Similar to Legionella pneumophila chaperone protein DnaK to codon 431 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 1.5e-08, 26.22% id in 328 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 611 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 2.3e-137, 58.09% id in 618 aa, and to Vibrio cholerae DnaK-related protein vc1373 to codon 611 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 2.9e-67, 39.74% id in 629 aa; Belongs to the heat shock protein 70 family.	Chaperone protein; Molecular chaperone. Has ATPase activity.	0.961
BPSS1096	BPSL1666	BPSS1096	BPSL1666	Similar to Legionella pneumophila chaperone protein DnaK to codon 347 SWALL:DNAK_LEGPN (SWALL:O32482) (644 aa) fasta scores: E(): 3e-06, 25.72% id in 346 aa, and to the full-length Vibrio cholerae DnaK-related protein vc1373 SWALL:Q9KS86 (EMBL:AE004217) (948 aa) fasta scores: E(): 1.3e-84, 47.05% id in 952 aa, and to Vibrio cholerae DnaK-related protein vc1374 to codon 606 SWALL:Q9KS85 (EMBL:AE004217) (631 aa) fasta scores: E(): 1.6e-46, 40.6% id in 628 aa.	Hypothetical protein; Very low similarities to any database matches to the full length of the CDS. The matches are reduced to the TPR domains that this CDS contains, e.g. Methanosarcina acetivorans TPR-domain containing protein ma1613 SWALL:Q8TQD1 (EMBL:AE010832) (1885 aa) fasta scores: E(): 1.6e-07, 21.22% id in 1164 aa.	0.615

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