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carB carB carA carA pyrB pyrB pyrB-2 pyrB-2 argF argF pyrD pyrD purF purF argG-2 argG-2 pyrF pyrF glt1 glt1 argG argG
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
carBSimilar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 68.93% id in 1088 aa, and to Ralstonia solanacearum carbamoyl-phosphate synthase large chain rsc1521 or rs03783 SWALL:Q8XZ83 (EMBL:AL646065) (1081 aa) fasta scores: E(): 0, 85.82% id in 1086 aa; Belongs to the CarB family. (1084 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase small chain; Similar to Escherichia coli, and Escherichia coli O157:H7 carbamoyl-phosphate synthase small chain CarA or PyrA or b0032 or z0037 or ecs0035 SWALL:CARA_ECOLI (SWALL:P00907) (382 aa) fasta scores: E(): 4.3e-94, 64.87% id in 373 aa, and to Ralstonia solanacearum carbamoyl-phosphate synthase small chain rsc1519 or rs03785 SWALL:CARA_RALSO (SWALL:Q8XZ85) (378 aa) fasta scores: E(): 6.4e-127, 83.28% id in 377 aa; Belongs to the CarA family.
 0.999
pyrB
Similar to Ralstonia solanacearum aspartate carbamoyltransferase PyrB or rsc0678 or rs01583 SWALL:PYRB_RALSO (SWALL:Q8Y1L2) (323 aa) fasta scores: E(): 1.7e-105, 88.64% id in 317 aa, and to Pseudomonas aeruginosa aspartate carbamoyltransferase PyrB or pa0402 SWALL:PYRB_PSEAE (SWALL:Q59653) (334 aa) fasta scores: E(): 4e-81, 69.8% id in 308 aa; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.998
pyrB-2
Similar to Burkholderia cepacia aspartate transcarbamoylase PyrB SWALL:Q9F9H3 (EMBL:AF192346) (431 aa) fasta scores: E(): 1.6e-157, 92.82% id in 432 aa, and to Pisum sativum aspartate carbamoyltransferase 2, chloroplast precursor PyrB2 SWALL:PYB2_PEA (SWALL:Q43087) (385 aa) fasta scores: E(): 2e-42, 43.61% id in 321 aa, and to Pisum sativum aspartate carbamoyltransferase 3, chloroplast precursor PyrB3 SWALL:PYB3_PEA (SWALL:Q43064) (391 aa) fasta scores: E(): 2.3e-42, 42.94% id in 333 aa; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
 0.998
argF
Putative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.989
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.988
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.988
argG-2
Similar to Streptomyces clavuligerus argininosuccinate synthase ArgG SWALL:ASSY_STRCL (SWALL:P50986) (397 aa) fasta scores: E(): 8.4e-49, 35.78% id in 394 aa, and to Thermoanaerobacter tengcongensis argininosuccinate synthase tte2494 SWALL:Q8R7C2 (EMBL:AE013190) (410 aa) fasta scores: E(): 1.9e-70, 44.92% id in 394 aa.
 
 0.987
pyrF
Similar to Ralstonia solanacearum orotidine 5'-phosphate decarboxylase rs00074 or rsc2773 SWALL:PYRF_RALSO (SWALL:P58642) (271 aa) fasta scores: E(): 1.5e-71, 72.86% id in 269 aa, and to Thermus thermophilus orotidine 5'-phosphate decarboxylase PyrF SWALL:PYRF_THETH (SWALL:P96076) (241 aa) fasta scores: E(): 8.9e-21, 39.35% id in 249 aa. Note: This CDS is longer in its N-terminal region than most of its database matches; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
  
 0.967
glt1
Glutamate synthase large subunit; Similar to Synechocystis sp. ferredoxin-dependent glutamate synthase 2 GltS or Sll1499 SWALL:GLTS_SYNY3 (SWALL:P55038) (1556 aa) fasta scores: E(): 0, 43.8% id in 1573 aa, and to Ralstonia solanacearum probable glutamate synthase GltB or Rsc2965 or Rs01332 SWALL:Q8XV66 (EMBL:AL646072) (1582 aa) fasta scores: E(): 0, 83.76% id in 1564 aa.
  
 
 0.966
argG
Similar to Escherichia coli argininosuccinate synthase ArgG SWALL:ASSY_ECOLI (SWALL:P22767) (446 aa) fasta scores: E(): 1.1e-138, 77.87% id in 443 aa, and to Neisseria meningitidis argininosuccinate synthase nma0303 SWALL:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 1.2e-144, 82.87% id in 438 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 0.961
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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