STRINGSTRING
BPSL2095 BPSL2095 ompR ompR BPSL1036 BPSL1036 BPSL1037 BPSL1037 BPSL2299 BPSL2299 BPSL1490 BPSL1490 BPSL3426 BPSL3426 BPSS1360 BPSS1360 BPSS1780 BPSS1780 BPSL0775 BPSL0775 BPSS1494 BPSS1494
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL2095Putative oxidative stress related two component system, sensor kinase; Similar to Escherichia coli osmolarity sensor protein EnvZ or OmpB or PerA or Tpo or b3404 SWALL:ENVZ_ECOLI (SWALL:P02933) (450 aa) fasta scores: E(): 7.8e-31, 32.3% id in 452 aa, and to Ralstonia solanacearum probable oxidative stress resistance two-component transmembrane sensor histidine kinase transcription regulator protein RisS or rsc1647 or rs04023 SWALL:Q8XYV9 (EMBL:AL646065) (453 aa) fasta scores: E(): 9.1e-95, 57.53% id in 438 aa. (452 aa)    
Predicted Functional Partners:
ompR
Oxidative stress related two component system, transcriptional regulator; Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, and Salmonella typhi transcriptional regulatory protein OmpR SWALL:OMPR_ECOLI (SWALL:P03025) (239 aa) fasta scores: E(): 8.7e-62, 68.67% id in 233 aa, and to Ralstonia solanacearum probable oxidative stress resistance two-component response regulator transcription regulator protein rsc1648 or rs04025 SWALL:Q8XYV8 (EMBL:AL646065) (240 aa) fasta scores: E(): 5.7e-82, 89.7% id in 233 aa.
 
 0.993
BPSL1036
Putative two-component system, response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, Salmonella typhimurium, and Salmonella typhi transcriptional regulatory protein OmpR SWALL:OMPR_ECOLI (SWALL:P03025) (239 aa) fasta scores: E(): 5.3e-42, 52.15% id in 232 aa, and to Ralstonia solanacearum probable two component response regulator transcription regulator protein rsp1196 or rs03140 SWALL:Q8XQM6 (EMBL:AL646083) (245 aa) fasta scores: E(): 7.1e-56, 63.33% id in 240 aa.
 
 0.981
BPSL1037
Putative two-component system, sensor kinase; Similar to Escherichia coli osmolarity sensor protein EnvZ or OmpB or PerA or Tpo or b3404 SWALL:ENVZ_ECOLI (SWALL:P02933) (450 aa) fasta scores: E(): 1.9e-24, 29.69% id in 431 aa, and to Ralstonia solanacearum probable two component transmembrane sensor kinase transcription regulator protein rsp1195 or rs03139 SWALL:Q8XQM7 (EMBL:AL646083) (431 aa) fasta scores: E(): 2.2e-59, 44.86% id in 428 aa.
  
  
 
0.924
BPSL2299
Putative dihydrolipoamide dehydrogenase; C-terminal region is similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 dihydrolipoamide dehydrogenase LpdA or Lpd SWALL:DLDH_ECOLI (SWALL:P00391) (473 aa) fasta scores: E(): 1.9e-93, 65.75% id in 473 aa. Full length CDS is similar to Ralstonia solanacearum probable dihydrolipoamide dehydrogenase rsc1603 or rs03965 SWALL:Q8XZ03 (EMBL:AL646065) (594 aa) fasta scores: E(): 2.1e-142, 76.88% id in 597 aa.
    
 0.867
BPSL1490
Putative membrane protein; Similar to Ralstonia solanacearum probable inner membrane transmembrane protein rsc1181 or rs05713 SWALL:Q8Y063 (EMBL:AL646063) (598 aa) fasta scores: E(): 5e-135, 52.92% id in 582 aa, and to Neisseria meningitidis putative inner membrane protein nma0497 SWALL:Q9JW86 (EMBL:AL162753) (558 aa) fasta scores: E(): 2.1e-23, 26.95% id in 575 aa.
 
   
 0.742
BPSL3426
Similar to Rhizobium loti two-component response regulator Mll7953 SWALL:Q984L3 (EMBL:AP003013) (223 aa) fasta scores: E(): 3.7e-35, 50.66% id in 227 aa, and to Salmonella typhimurium transcriptional regulatory protein TctD or Stm2785 SWALL:TCTD_SALTY (SWALL:P22104) (224 aa) fasta scores: E(): 1.1e-29, 42.34% id in 222 aa.
 
 
 0.725
BPSS1360
Putative two-component sensor kinase protein; C-terminus is similar to the C-terminal regions of Anabaena sp. cyanobacterial phytochrome A AphA or ALR3157 SWALL:PHYA_ANASP (SWALL:Q9LCC2) (765 aa) fasta scores: E(): 3.5e-45, 54.78% id in 261 aa, and to Methanosarcina acetivorans sensory transduction histidine kinase MA1270 SWALL:Q8TRB0 (EMBL:AE010795) (1456 aa) fasta scores: E(): 4.8e-62, 41.14% id in 508 aa.
 
 
 
0.723
BPSS1780
Putative membrane protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc2234 or rs01365 SWALL:Q8XX82 (EMBL:AL646069) (265 aa) fasta scores: E(): 2e-41, 45.92% id in 270 aa.
  
     0.711
BPSL0775
Similar to Bordetella pertussis transcriptional regulatory protein, putative BasR SWALL:Q9S3M3 (EMBL:AJ132741) (223 aa) fasta scores: E(): 3.2e-37, 53.6% id in 222 aa, and to Ralstonia solanacearum probable response regulator transcription regulator protein rsc0550 or rs04916 SWALL:Q8Y1Y7 (EMBL:AL646059) (232 aa) fasta scores: E(): 2.1e-63, 78.94% id in 228 aa, and to Agrobacterium tumefaciens two component response regulator TctD SWALL:Q8UCL7 (EMBL:AE009193) (245 aa) fasta scores: E(): 1.7e-37, 51.81% id in 220 aa.
 
 
 0.705
BPSS1494
Putative two-component response regulator protein; Similar to Rhizobium sp LcrB protein SWALL:Q53167 (EMBL:M38698) (238 aa) fasta scores: E(): 9.9e-34, 43.16% id in 234 aa, and to Agrobacterium tumefaciens Tiorf152 protein SWALL:BAA87777 (EMBL:AB016260) (253 aa) fasta scores: E(): 3.5e-32, 41% id in 239 aa, and to Agrobacterium tumefaciens regulatory protein VirG or atu6178 or agr_pti_15 SWALL:VIRG_AGRT5 (SWALL:P07545) (253 aa) fasta scores: E(): 3.5e-32, 41% id in 239 aa.
 
 
 0.702
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.