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ppsA ppsA eno eno maeB maeB BPSL3242 BPSL3242 lldA lldA pdhA pdhA aceE aceE ppc ppc pckG pckG poxB poxB pykA pykA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (799 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.957
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 5.4e-181, 61.8% id in 754 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein rsc2767 or rs00080 SWALL:Q8XVR2 (EMBL:AL646071) (781 aa) fasta scores: E(): 0, 78.28% id in 760 aa.
  
 
 0.945
BPSL3242
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 1.6e-184, 63.72% id in 758 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein MaeB1 or Rsc2123 or Rs03232 SWALL:Q8XXJ0 (EMBL:AL646068) (773 aa) fasta scores: E(): 5.7e-194, 67.86% id in 753 aa; Belongs to the malic enzymes family.
  
 
 0.945
lldA
Similar to Neisseria meningitidis L-lactate dehydrogenase LldA or nma1592 SWALL:Q9JTX1 (EMBL:AL162756) (390 aa) fasta scores: E(): 8.4e-92, 61.93% id in 373 aa, and to Pseudomonas aeruginosa L-lactate dehydrogenase LldA or pa2382 SWALL:Q9I197 (EMBL:AE004664) (383 aa) fasta scores: E(): 1.4e-103, 72.41% id in 377 aa, and to Agrobacterium tumefaciens L-lactate dehydrogenase LldA or atu2318 or agr_c_4216 SWALL:Q8UD10 (EMBL:AE009181) (382 aa) fasta scores: E(): 3.7e-94, 64.17% id in 374 aa.
     
 0.936
pdhA
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.931
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.931
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.930
pckG
Phosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.922
poxB
Similar to Escherichia coli pyruvate dehydrogenase [cytochrome] PoxB or b0871 SWALL:POXB_ECOLI (SWALL:P07003) (572 aa) fasta scores: E(): 5.4e-146, 64.44% id in 571 aa, and to Xanthomonas axonopodis pyruvate dehydrogenase PoxB or xac0224 SWALL:AAM35116 (EMBL:AE011647) (575 aa) fasta scores: E(): 9.1e-152, 66.66% id in 570 aa; Belongs to the TPP enzyme family.
    
 0.921
pykA
Putative pyruvate kinase II protein; Similar to Pseudomonas hydrogenothermophila pyruvate kinase Pyk SWALL:Q9LBF0 (EMBL:AB042618) (473 aa) fasta scores: E(): 5.5e-91, 58.82% id in 476 aa, and to Ralstonia solanacearum probable pyruvate kinase II protein rsc0572 or rs04893 SWALL:Q8Y1W5 (EMBL:AL646060) (479 aa) fasta scores: E(): 2.9e-131, 78.49% id in 479 aa.
    
 0.918
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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