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fabI fabI fabF fabF fabZ fabZ fabD fabD fabV fabV BPSS0300 BPSS0300 BPSL1335 BPSL1335 fabG fabG FabG FabG BPSS0721 BPSS0721 BPSL1167 BPSL1167
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fabIEnoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, and Escherichia coli O157:H7 enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or b1288 or z2512 or ecs1861 SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 1.2e-58, 62.45% id in 261 aa, and to Ralstonia solanacearum probable enoyl-[acyl-carrier-protein] reductase rsc1172 or rs04528 SWALL:Q8Y072 (EMBL:AL646063) (264 aa) fasta scores: E(): 1.4e-74, 78.12% id in 256 aa. (263 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.986
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.981
fabD
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase fabD or TfpA SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 4.4e-56, 54.72% id in 307 aa, and to Ralstonia solanacearum probable malonyl CoA-[acyl-carrier-protein] transacylase rsc1051 or rs04178 SWALL:Q8Y0J3 (EMBL:AL646062) (309 aa) fasta scores: E(): 8.2e-89, 81.31% id in 305 aa.
 
 
 0.979
fabV
Conserved hypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.
     
 0.972
BPSS0300
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 2.6e-24, 34.75% id in 305 aa, and to Bacillus subtilis PksC protein SWALL:O34825 (EMBL:Z99112) (288 aa) fasta scores: E(): 1.3e-39, 43.35% id in 286 aa.
 
 
 0.968
BPSL1335
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 2.6e-14, 29.66% id in 300 aa, and to Xanthomonas campestris malonyl CoA-ACP transacylase MdcH or xcc3615 SWALL:AAM42885 (EMBL:AE012482) (306 aa) fasta scores: E(): 3.1e-40, 48.36% id in 306 aa, and to.
 
 
 0.962
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.929
FabG
Putative dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 7-alpha-hydroxysteroid dehydrogenase HdhA or HsdH or b1619 or z2624 or ecs2327 SWALL:HDHA_ECOLI (SWALL:P25529) (255 aa) fasta scores: E(): 8.5e-27, 40.96% id in 249 aa, and to Ralstonia solanacearum probable toluenesulfonate zinc-independent alcohol dehydrogenase oxidoreductase protein rsc2351 or rs01195 SWALL:Q8XWW9 (EMBL:AL646069) (252 aa) fasta scores: E(): 7.7e-70, 71.42% id in 252 aa.
  
 
 0.925
BPSS0721
Putative enoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 2.1e-37, 42.4% id in 250 aa, and to Brucella melitensis enoyl-(acyl-carrier-protein) reductase [NADH] bmei1512 SWALL:Q8YFK8 (EMBL:AE009587) (272 aa) fasta scores: E(): 5.5e-42, 47.01% id in 251 aa.
  
  
0.912
BPSL1167
Putative dehydrogenase; Similar to Xanthomonas axonopodis pv. citri str. 306 oxidoreductase xac0384 SWALL:AAM35276 (EMBL:AE011664) (260 aa) fasta scores: E(): 1.7e-66, 71.53% id in 260 aa, and to Ralstonia solanacearum probable dehydrogenase/reductase oxidoreductase protein rsc2186 or rs01413 SWALL:Q8XXC9 (EMBL:AL646068) (263 aa) fasta scores: E(): 3e-61, 67.3% id in 263 aa.
  
 
 0.909
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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