STRINGSTRING
ask ask asd asd hom hom asnO asnO argG-2 argG-2 BPSL0682 BPSL0682 BPSS0677 BPSS0677 thrC thrC argG argG purA purA nadB nadB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
askAspartokinase; Similar to Mycobacterium smegmatis aspartokinase Ask SWALL:AK_MYCSM (SWALL:P41403) (421 aa) fasta scores: E(): 2e-66, 47.96% id in 417 aa, and to Methylobacillus glycogenes aspartate kinase LysC SWALL:Q8RU02 (EMBL:AB038354) (408 aa) fasta scores: E(): 7.2e-104, 71.56% id in 415 aa; Belongs to the aspartokinase family. (416 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.992
hom
Similar to Pseudomonas aeruginosa homoserine dehydrogenase Hom or pa3736 SWALL:DHOM_PSEAE (SWALL:P29365) (434 aa) fasta scores: E(): 1e-98, 63.12% id in 442 aa, and to Ralstonia solanacearum probable homoserine dehydrogenase oxidoreductase protein rsc1327 or rs02849 SWALL:Q8XZR8 (EMBL:AL646064) (439 aa) fasta scores: E(): 8.2e-121, 78.73% id in 442 aa.
 
 0.917
asnO
Similar to Bacillus subtilis asparagine synthetase [glutamine-hydrolyzing] 3 AsnO SWALL:ASNO_BACSU (SWALL:O05272) (614 aa) fasta scores: E(): 1.6e-68, 42.01% id in 626 aa, and to Streptomyces aureofaciens asparagine synthase homolog TcsG SWALL:Q9FAR2 (EMBL:AB039379) (609 aa) fasta scores: E(): 2.6e-128, 54.76% id in 619 aa.
  
 
 0.889
argG-2
Similar to Streptomyces clavuligerus argininosuccinate synthase ArgG SWALL:ASSY_STRCL (SWALL:P50986) (397 aa) fasta scores: E(): 8.4e-49, 35.78% id in 394 aa, and to Thermoanaerobacter tengcongensis argininosuccinate synthase tte2494 SWALL:Q8R7C2 (EMBL:AE013190) (410 aa) fasta scores: E(): 1.9e-70, 44.92% id in 394 aa.
 
 
 0.878
BPSL0682
Similar to Escherichia coli asparagine synthetase B [glutamine-hydrolyzing] asnB or b0674 SWALL:ASNB_ECOLI (SWALL:P22106) (553 aa) fasta scores: E(): 7.9e-21, 32.63% id in 524 aa, and to Lactococcus lactis asparagine synthetase B asnB or ll0352 SWALL:Q9CIK5 (EMBL:AE006272) (530 aa) fasta scores: E(): 4.7e-30, 30.04% id in 476 aa, and to Caenorhabditis elegans M02d8.4 protein m02d8.4 SWALL:Q21463 (EMBL:U41034) (567 aa) fasta scores: E(): 6e-28, 30.66% id in 525 aa.
  
 
 0.865
BPSS0677
Putative asparagine synthetase; Similar to Burkholderia cepacia genomovar III putative asparagine synthetase SWALL:Q8VP10 (EMBL:AY028431) (656 aa) fasta scores: E(): 6e-206, 74.54% id in 656 aa. N-terminal region is similar to the N-terminal region of Bacillus subtilis asparagine synthetase [glutamine-hydrolyzing] 2 AsnH SWALL:ASNH_BACSU (SWALL:P42113) (747 aa) fasta scores: E(): 4.6e-23, 27.93% id in 605 aa.
  
 
 0.865
thrC
Threonine synthase; Similar to Corynebacterium glutamicum threonine synthase ThrC or cgl2220 SWALL:THRC_CORGL (SWALL:P23669) (481 aa) fasta scores: E(): 8.6e-100, 57.97% id in 483 aa, and to Ralstonia solanacearum probable threonine synthase protein rsc1328 or rs02850 SWALL:Q8XZR7 (EMBL:AL646064) (481 aa) fasta scores: E(): 5.1e-144, 76.55% id in 482 aa.
  
 
 0.861
argG
Similar to Escherichia coli argininosuccinate synthase ArgG SWALL:ASSY_ECOLI (SWALL:P22767) (446 aa) fasta scores: E(): 1.1e-138, 77.87% id in 443 aa, and to Neisseria meningitidis argininosuccinate synthase nma0303 SWALL:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 1.2e-144, 82.87% id in 438 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
 
 0.860
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.840
nadB
Putative L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.819
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.