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dapA dapA dapB dapB asd asd hom hom BPSL0936 BPSL0936 dapA-2 dapA-2 lysA lysA dapF dapF BPSS0303 BPSS0303 BPSL2261 BPSL2261 trpS-2 trpS-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
 
 0.993
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.947
hom
Similar to Pseudomonas aeruginosa homoserine dehydrogenase Hom or pa3736 SWALL:DHOM_PSEAE (SWALL:P29365) (434 aa) fasta scores: E(): 1e-98, 63.12% id in 442 aa, and to Ralstonia solanacearum probable homoserine dehydrogenase oxidoreductase protein rsc1327 or rs02849 SWALL:Q8XZR8 (EMBL:AL646064) (439 aa) fasta scores: E(): 8.2e-121, 78.73% id in 442 aa.
 
 
 0.939
BPSL0936
Putative dihydrodipicolinate synthetase; Similar to Methanopyrus kandleri dihydrodipicolinate synthase DapA or mk1607 SWALL:Q8TUZ4 (EMBL:AE010450) (300 aa) fasta scores: E(): 1.7e-25, 31.48% id in 289 aa, and to Pseudomonas aeruginosa probable dihydrodipicolinate synthetase pa0223 SWALL:Q9I6R5 (EMBL:AE004460) (293 aa) fasta scores: E(): 4e-68, 61.43% id in 293 aa, and to Vibrio sp. CH-291 hypothetical protein SWALL:Q93IK7 (EMBL:AJ314791) (295 aa) fasta scores: E(): 9.2e-63, 57.58% id in 290 aa.
  
  
0.925
dapA-2
Dihydrodipicolinate synthetase family protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 
0.921
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.776
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.759
BPSS0303
Similar to Pseudomonas aeruginosa diaminopimelate decarboxylase pa5277 SWALL:DCDA_PSEAE (SWALL:P19572) (415 aa) fasta scores: E(): 1.6e-21, 31.68% id in 404 aa, and to Escherichia coli diaminopimelate decarboxylase LysA or b2838 SWALL:DCDA_ECOLI (SWALL:P00861) (420 aa) fasta scores: E(): 4.8e-19, 31.76% id in 403 aa.
 
  
 0.736
BPSL2261
Putative membrane protein; Similar to Ralstonia solanacearum probable integral membrane transmembrane protein rsc1142 or rs04611 SWALL:Q8Y0A2 (EMBL:AL646062) (225 aa) fasta scores: E(): 9.8e-49, 56.33% id in 213 aa, and to Neisseria meningitidis conserved hypothetical integral membrane protein nma1986 SWALL:Q9JT39 (EMBL:AL162757) (212 aa) fasta scores: E(): 1.6e-25, 40.67% id in 209 aa.
       0.675
trpS-2
Putative tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.674
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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