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pdhA pdhA BPSL2299 BPSL2299 pdhB pdhB maeB maeB BPSL3242 BPSL3242 odhL odhL lpdV lpdV lldA lldA ppsA ppsA pykA pykA pyk pyk
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
pdhAPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (898 aa)    
Predicted Functional Partners:
BPSL2299
Putative dihydrolipoamide dehydrogenase; C-terminal region is similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 dihydrolipoamide dehydrogenase LpdA or Lpd SWALL:DLDH_ECOLI (SWALL:P00391) (473 aa) fasta scores: E(): 1.9e-93, 65.75% id in 473 aa. Full length CDS is similar to Ralstonia solanacearum probable dihydrolipoamide dehydrogenase rsc1603 or rs03965 SWALL:Q8XZ03 (EMBL:AL646065) (594 aa) fasta scores: E(): 2.1e-142, 76.88% id in 597 aa.
 
 0.998
pdhB
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.995
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 5.4e-181, 61.8% id in 754 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein rsc2767 or rs00080 SWALL:Q8XVR2 (EMBL:AL646071) (781 aa) fasta scores: E(): 0, 78.28% id in 760 aa.
  
 
 0.949
BPSL3242
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 1.6e-184, 63.72% id in 758 aa, and to Ralstonia solanacearum putative NADP-dependent malic enzyme oxidoreductase protein MaeB1 or Rsc2123 or Rs03232 SWALL:Q8XXJ0 (EMBL:AL646068) (773 aa) fasta scores: E(): 5.7e-194, 67.86% id in 753 aa; Belongs to the malic enzymes family.
  
 
 0.949
odhL
Similar to Alcaligenes eutrophus dihydrolipoamide dehydrogenase OdhL SWALL:DLDH_ALCEU (SWALL:P52992) (474 aa) fasta scores: E(): 9.7e-132, 76.93% id in 477 aa, and to Ralstonia solanacearum probable dihydrolipoamide dehydrogenase rsc1271 or rs02809 SWALL:Q8XZX4 (EMBL:AL646063) (478 aa) fasta scores: E(): 2.9e-134, 77.35% id in 477 aa.
  
 
 0.940
lpdV
Similar to Pseudomonas putida dihydrolipoamide dehydrogenase LpdV SWALL:DLD1_PSEPU (SWALL:P09063) (459 aa) fasta scores: E(): 9.9e-115, 69.09% id in 466 aa, and to Pseudomonas aeruginosa lipoamide dehydrogenase-Val pa2250 SWALL:Q9I1L9 (EMBL:AE004650) (464 aa) fasta scores: E(): 2.6e-123, 71.24% id in 466 aa.
  
 
 0.940
lldA
Similar to Neisseria meningitidis L-lactate dehydrogenase LldA or nma1592 SWALL:Q9JTX1 (EMBL:AL162756) (390 aa) fasta scores: E(): 8.4e-92, 61.93% id in 373 aa, and to Pseudomonas aeruginosa L-lactate dehydrogenase LldA or pa2382 SWALL:Q9I197 (EMBL:AE004664) (383 aa) fasta scores: E(): 1.4e-103, 72.41% id in 377 aa, and to Agrobacterium tumefaciens L-lactate dehydrogenase LldA or atu2318 or agr_c_4216 SWALL:Q8UD10 (EMBL:AE009181) (382 aa) fasta scores: E(): 3.7e-94, 64.17% id in 374 aa.
     
 0.934
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.931
pykA
Putative pyruvate kinase II protein; Similar to Pseudomonas hydrogenothermophila pyruvate kinase Pyk SWALL:Q9LBF0 (EMBL:AB042618) (473 aa) fasta scores: E(): 5.5e-91, 58.82% id in 476 aa, and to Ralstonia solanacearum probable pyruvate kinase II protein rsc0572 or rs04893 SWALL:Q8Y1W5 (EMBL:AL646060) (479 aa) fasta scores: E(): 2.9e-131, 78.49% id in 479 aa.
  
 
 0.918
pyk
Pyruvate kinase; Similar to Bacillus stearothermophilus pyruvate kinase Pyk SWALL:KPYK_BACST (SWALL:Q02499) (587 aa) fasta scores: E(): 1.7e-60, 41.27% id in 470 aa, and to Pseudomonas aeruginosa pyruvate kinase I PykF or pa1498 SWALL:Q9I3L4 (EMBL:AE004578) (477 aa) fasta scores: E(): 1.5e-83, 55.57% id in 466 aa.
  
 
 0.918
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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