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argM argM astB astB astD astD argA argA argC argC argJ argJ BPSL2388 BPSL2388 BPSL2389 BPSL2389 astE astE argB argB argG-2 argG-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
argMSimilar to Escherichia coli succinylornithine transaminase ArgM or AstC or CstC SWALL:ARGM_ECOLI (SWALL:P77581) (406 aa) fasta scores: E(): 5.3e-93, 61.38% id in 404 aa, and to Vibrio cholerae acetylornithine aminotransferase vc2618 SWALL:Q9KNW2 (EMBL:AE004328) (403 aa) fasta scores: E(): 1.4e-94, 60.55% id in 398 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (410 aa)    
Predicted Functional Partners:
astB
Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).
 
 
 0.987
astD
Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
 
 0.975
argA
Putative amino-acid acetyltransferase; Similar to Escherichia coli, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.5e-76, 46.89% id in 435 aa, and to Ralstonia solanacearum probable amino-acid acetyltransferase protein rsc1250 or rs02762 SWALL:Q8XZZ5 (EMBL:AL646063) (451 aa) fasta scores: E(): 3.6e-123, 71.71% id in 449 aa. CDS is extended at the N-terminus in comparison to some orthologues. Possible alternative translational start site.
 
 
 0.959
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
 
 
 0.929
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.907
BPSL2388
Putative arginine N-succinyltransferase, beta chain; Similar to Escherichia coli, and Escherichia coli O157:H7 arginine N-succinyltransferase AstA SWALL:ASTA_ECOLI (SWALL:P76218) (344 aa) fasta scores: E(): 7.4e-60, 46.74% id in 338 aa, and to Pseudomonas aeruginosa arginine N-succinyltransferase, beta chain AruA or pa0897 SWALL:ASTG_PSEAE (SWALL:P80358) (340 aa) fasta scores: E(): 3.9e-53, 42.22% id in 341 aa, and to Pseudomonas aeruginosa arginine N-succinyltransferase, alpha chain AstA or AruF or pa0896 SWALL:ASTA_PSEAE (SWALL:P80357) (338 aa) fasta scores: E(): 2e-39, 37.13% id in [...]
 
  
 0.888
BPSL2389
Similar to Pseudomonas aeruginosa arginine N-succinyltransferase, alpha chain AstA or AruF or pa0896 SWALL:ASTA_PSEAE (SWALL:P80357) (338 aa) fasta scores: E(): 1e-52, 44.34% id in 336 aa, and to Escherichia coli, and Escherichia coli O157:H7 arginine N-succinyltransferase AstA SWALL:ASTA_ECOLI (SWALL:P76218) (344 aa) fasta scores: E(): 1.1e-36, 35.5% id in 338 aa, and to Pseudomonas aeruginosa arginine N-succinyltransferase, beta chain AruG or pa0897 SWALL:ASTG_PSEAE (SWALL:P80358) (340 aa) fasta scores: E(): 2e-36, 36.41% id in 346 aa.
 
  
 0.887
astE
Putative glutathione S-transferase (fragment); Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
 
  
 0.874
argB
Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.839
argG-2
Similar to Streptomyces clavuligerus argininosuccinate synthase ArgG SWALL:ASSY_STRCL (SWALL:P50986) (397 aa) fasta scores: E(): 8.4e-49, 35.78% id in 394 aa, and to Thermoanaerobacter tengcongensis argininosuccinate synthase tte2494 SWALL:Q8R7C2 (EMBL:AE013190) (410 aa) fasta scores: E(): 1.9e-70, 44.92% id in 394 aa.
 
 
 0.835
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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