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aroG aroG aroB aroB aroG-2 aroG-2 tktA tktA cbbA cbbA BPSL2222 BPSL2222 BPSL2223 BPSL2223 pheA pheA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
aroGPutative phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
  
 0.934
aroG-2
Putative phospho-2-dehydro-3-deoxyheptonate aldolase, phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
  
  
 
0.902
tktA
Transketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or b2935 SWALL:TKT1_ECOLI (SWALL:P27302) (663 aa) fasta scores: E(): 4.8e-167, 63.48% id in 671 aa, and to Ralstonia solanacearum probable transketolase protein rsc2750 or rs00104 SWALL:Q8XVS9 (EMBL:AL646071) (675 aa) fasta scores: E(): 4.5e-192, 72.99% id in 674 aa; Belongs to the transketolase family.
     
 0.831
cbbA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
     
 0.817
BPSL2222
Putative transketolase; Similar to Thermoplasma acidophilum probable transketolase ta0617 SWALL:Q9HKI2 (EMBL:AL445064) (316 aa) fasta scores: E(): 2.6e-24, 32.67% id in 303 aa, and to Pyrococcus abyssi transketolase C-terminal section Tkt2 or pab0296 SWALL:Q9V1I1 (EMBL:AJ248284) (317 aa) fasta scores: E(): 9.6e-22, 32.65% id in 294 aa.
    
  0.816
BPSL2223
Putative transketolase; Similar to Fusobacterium nucleatum transketolase subunit A fn0294 SWALL:Q8RGJ9 (EMBL:AE010542) (270 aa) fasta scores: E(): 2.2e-33, 42.53% id in 268 aa, and to Methanococcus jannaschii putative transketolase N-terminal section mj0681 SWALL:TKTN_METJA (SWALL:Q58094) (274 aa) fasta scores: E(): 2.5e-29, 38.62% id in 277 aa.
    
  0.816
pheA
Similar to many involved in Phenylalanine biosynthesis: Neisseria gonorrhoeae P-protein [includes: chorismate mutase (EC 5.4.99.5) (cm); prephenate dehydratase (EC 4.2.1.51) (pdt)] PheA SWALL:PHEA_NEIGO (SWALL:Q9ZHY3) (362 aa) fasta scores: E(): 1.8e-64, 50% id in 362 aa, Ralstonia solanacearum probable bifunctional protein: chorismate mutase and prephenate dehydratase PheA or rsc0904 or rs04511 SWALL:Q8Y0Y9 (EMBL:AL646061) (371 aa) fasta scores: E(): 9.6e-85, 61.45% id in 358 aa and to Pseudomonas stutzeri p-protein PheA SWALL:PHEA_PSEST (SWALL:P27603) (365 aa) fasta scores: E(): 3.4e [...]
  
  
 0.642
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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