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katG katG katE katE katB katB BPSL0071 BPSL0071 hisC hisC tyrB tyrB tyrB1 tyrB1 tyrB2 tyrB2 hisC1 hisC1 BPSL1724 BPSL1724 kynU kynU
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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katGCatalase-peroxidase protein; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, isoniazid hydrazine lyase and isonicotinoyl-NAD synthase activity. (748 aa)    
Predicted Functional Partners:
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
    
 0.972
katB
Pfam match to entry PF00072 response_reg, Response regulator receiver domain, score 85.7, E-value 6.3e-23; Belongs to the catalase family.
    
 0.932
BPSL0071
Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
    
 0.916
hisC
Similar to Streptomyces coelicolor histidinol-phosphate aminotransferase 1 HisC1 or HisC or SCO2053 or SC4G6.22c SWALL:HI81_STRCO (SWALL:P16246) (369 aa) fasta scores: E(): 9.9e-30, 36.63% id in 363 aa, and to Ralstonia solanacearum histidinol-phosphate aminotransferase 1 HisC1 or Rsc2951 or Rs00135 SWALL:HI81_RALSO (SWALL:Q8XV80) (374 aa) fasta scores: E(): 1.9e-87, 67.13% id in 353 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.908
tyrB
Similar to Escherichia coli aromatic-amino-acid aminotransferase TyrB or b4054 SWALL:TYRB_ECOLI (SWALL:P04693) (397 aa) fasta scores: E(): 1.3e-80, 54.63% id in 399 aa, and to Pseudomonas aeruginosa aspartate aminotransferase AspC or pa3139 SWALL:AAT_PSEAE (SWALL:P72173) (398 aa) fasta scores: E(): 2.6e-111, 73.86% id in 398 aa. Note: Also similar to BPSS0808 (401 aa) fasta scores: E(): 7.1e-72, 53.149% identity in 397 aa overlap.
     
 0.908
tyrB1
Similar to Escherichia coli aromatic-amino-acid aminotransferase TyrB SWALL:TYRB_ECOLI (SWALL:P04693) (397 aa) fasta scores: E(): 2.1e-90, 58.43% id in 397 aa, and to Klebsiella pneumoniae tyrosine aminotransferase TyrB SWALL:O85746 (EMBL:AF074934) (397 aa) fasta scores: E(): 2.8e-89, 57.17% id in 397 aa. Similar to BPSS2200, 55.556% identity in 396 aa overlap, and to BPSS0355, 53.149% identity in 397 aa overlap. Note: Also similar to BPSS2200 TyrB2 (405 aa)fasta scores: E(): 4.4e-79, 55.556% identity in 396 aa overlap;. Note: Also similar to BPSS2200 (444 aa) fasta scores: E(): 4.4e-7 [...]
     
 0.908
tyrB2
Similar to Escherichia coli aromatic-amino-acid aminotransferase TyrB or b4054 SWALL:TYRB_ECOLI (SWALL:P04693) (397 aa) fasta scores: E(): 7.1e-92, 58.69% id in 397 aa, and to Pseudomonas putida aromatic-amino-acid aminotransferase TyrB-2 or pp3590 SWALL:AAN69190 (EMBL:AE016787) (398 aa) fasta scores: E(): 3.5e-91, 58.54% id in 398 aa. Note: Also similar to BPSS0808 TyrB1 (401 aa) fasta scores: E(): 1.1e-74, 55.556% identity in 396 aa overlap.
     
 0.908
hisC1
Similar to Lactococcus lactis histidinol-phosphate aminotransferase HisC SWALL:HIS8_LACLA (SWALL:Q02135) (360 aa) fasta scores: E(): 1.3e-55, 46.57% id in 350 aa, and to Rhizobium meliloti histidinol-phosphate aminotransferase 2 r03268 or smc03885 SWALL:HI82_RHIME (SWALL:Q92L21) (351 aa) fasta scores: E(): 2e-76, 61.01% id in 354 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.905
BPSL1724
Similar to Anabaena sp. histidinol-phosphate aminotransferase 1 HisC1 or alr2092 SWALL:HI81_ANASP (SWALL:Q8YV89) (353 aa) fasta scores: E(): 3.1e-20, 31.17% id in 324 aa, and to Halobacterium volcanii histidinol-phosphate aminotransferase HisC SWALL:HIS8_HALVO (SWALL:P17736) (361 aa) fasta scores: E(): 7.6e-18, 30.74% id in 322 aa.
     
 0.905
kynU
Conserved hypothetical protein; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
     
  0.900
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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