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dapB dapB dapA dapA dapA-2 dapA-2 BPSL0936 BPSL0936 dapD dapD BPSS0331 BPSS0331 asd asd ask ask dnaJ dnaJ mgsA mgsA dapF dapF
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (268 aa)    
Predicted Functional Partners:
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.993
dapA-2
Dihydrodipicolinate synthetase family protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.992
BPSL0936
Putative dihydrodipicolinate synthetase; Similar to Methanopyrus kandleri dihydrodipicolinate synthase DapA or mk1607 SWALL:Q8TUZ4 (EMBL:AE010450) (300 aa) fasta scores: E(): 1.7e-25, 31.48% id in 289 aa, and to Pseudomonas aeruginosa probable dihydrodipicolinate synthetase pa0223 SWALL:Q9I6R5 (EMBL:AE004460) (293 aa) fasta scores: E(): 4e-68, 61.43% id in 293 aa, and to Vibrio sp. CH-291 hypothetical protein SWALL:Q93IK7 (EMBL:AJ314791) (295 aa) fasta scores: E(): 9.2e-63, 57.58% id in 290 aa.
 
 
 0.982
dapD
Similar to Escherichia coli 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase DapD or b0166 SWALL:DAPD_ECOLI (SWALL:P03948) (274 aa) fasta scores: E(): 1.6e-79, 76.75% id in 271 aa, and to Ralstonia solanacearum probable 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase protein rsc1393 or rs04676 SWALL:Q8XZK2 (EMBL:AL646064) (275 aa) fasta scores: E(): 1.3e-92, 85.81% id in 275 aa; Belongs to the transferase hexapeptide repeat family.
 
 
 0.968
BPSS0331
Similar to Prochlorococcus marinus dihydrodipicolinate synthase DapA SWALL:DAPA_PROMA (SWALL:P49423) (302 aa) fasta scores: E(): 1.1e-19, 30.24% id in 291 aa, and to Pseudomonas aeruginosa probable dihydrodipicolinate synthetase pa1254 SWALL:Q9I490 (EMBL:AE004555) (305 aa) fasta scores: E(): 3.3e-92, 73.52% id in 306 aa.
 
 
 0.841
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
  
 0.793
ask
Aspartokinase; Similar to Mycobacterium smegmatis aspartokinase Ask SWALL:AK_MYCSM (SWALL:P41403) (421 aa) fasta scores: E(): 2e-66, 47.96% id in 417 aa, and to Methylobacillus glycogenes aspartate kinase LysC SWALL:Q8RU02 (EMBL:AB038354) (408 aa) fasta scores: E(): 7.2e-104, 71.56% id in 415 aa; Belongs to the aspartokinase family.
 
  
 0.790
dnaJ
Putative DnaJ chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
 
  
 0.785
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
    0.774
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
   
 0.743
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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