STRINGSTRING
gapA gapA pgk pgk tpiA tpiA cbbA cbbA eno eno tktA tktA pgi pgi zwf zwf talB talB BPSL2222 BPSL2222 BPSL2223 BPSL2223
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
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Cooccurrence
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[Homology]
Score
gapASimilar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 AapA or Gap SWALL:G3P1_BACSU (SWALL:P09124) (334 aa) fasta scores: E(): 2.7e-71, 60.06% id in 333 aa, and to Alcaligenes eutrophus glyceraldehyde 3-phosphate dehydrogenase, plasmid CbbGP SWALL:G3PP_ALCEU (SWALL:P50322) (336 aa) fasta scores: E(): 5.1e-112, 84.52% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)    
Predicted Functional Partners:
pgk
Similar to Escherichia coli phosphoglycerate kinase Pgk or b2926 SWALL:PGK_ECOLI (SWALL:P11665) (386 aa) fasta scores: E(): 1.8e-80, 63.7% id in 394 aa, and to Ralstonia solanacearum phosphoglycerate kinase Pgk or rsc0571 or rs04894 SWALL:Q8Y1W6 (EMBL:AL646060) (419 aa) fasta scores: E(): 1.7e-115, 85.64% id in 397 aa.
 
 0.999
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.999
cbbA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 0.991
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.991
tktA
Transketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or b2935 SWALL:TKT1_ECOLI (SWALL:P27302) (663 aa) fasta scores: E(): 4.8e-167, 63.48% id in 671 aa, and to Ralstonia solanacearum probable transketolase protein rsc2750 or rs00104 SWALL:Q8XVS9 (EMBL:AL646071) (675 aa) fasta scores: E(): 4.5e-192, 72.99% id in 674 aa; Belongs to the transketolase family.
  
 0.989
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 2.5e-100, 49.9% id in 543 aa, and to Deinococcus radiodurans glucose-6-phosphate isomerase dr1742 SWALL:G6PI_DEIRA (SWALL:Q9RTL8) (541 aa) fasta scores: E(): 7.5e-120, 57.22% id in 540 aa.
 
 
 0.982
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 0.927
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.926
BPSL2222
Putative transketolase; Similar to Thermoplasma acidophilum probable transketolase ta0617 SWALL:Q9HKI2 (EMBL:AL445064) (316 aa) fasta scores: E(): 2.6e-24, 32.67% id in 303 aa, and to Pyrococcus abyssi transketolase C-terminal section Tkt2 or pab0296 SWALL:Q9V1I1 (EMBL:AJ248284) (317 aa) fasta scores: E(): 9.6e-22, 32.65% id in 294 aa.
    
 0.922
BPSL2223
Putative transketolase; Similar to Fusobacterium nucleatum transketolase subunit A fn0294 SWALL:Q8RGJ9 (EMBL:AE010542) (270 aa) fasta scores: E(): 2.2e-33, 42.53% id in 268 aa, and to Methanococcus jannaschii putative transketolase N-terminal section mj0681 SWALL:TKTN_METJA (SWALL:Q58094) (274 aa) fasta scores: E(): 2.5e-29, 38.62% id in 277 aa.
    
 0.922
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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