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tktA tktA talB talB gapA gapA rpiA rpiA BPSL3048 BPSL3048 tpiA tpiA pgi pgi cbbA cbbA fbp fbp prs prs eno eno
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
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[Homology]
Score
tktATransketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or b2935 SWALL:TKT1_ECOLI (SWALL:P27302) (663 aa) fasta scores: E(): 4.8e-167, 63.48% id in 671 aa, and to Ralstonia solanacearum probable transketolase protein rsc2750 or rs00104 SWALL:Q8XVS9 (EMBL:AL646071) (675 aa) fasta scores: E(): 4.5e-192, 72.99% id in 674 aa; Belongs to the transketolase family. (675 aa)    
Predicted Functional Partners:
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
 
 0.995
gapA
Similar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 AapA or Gap SWALL:G3P1_BACSU (SWALL:P09124) (334 aa) fasta scores: E(): 2.7e-71, 60.06% id in 333 aa, and to Alcaligenes eutrophus glyceraldehyde 3-phosphate dehydrogenase, plasmid CbbGP SWALL:G3PP_ALCEU (SWALL:P50322) (336 aa) fasta scores: E(): 5.1e-112, 84.52% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.989
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 0.982
BPSL3048
Similar to Alcaligenes eutrophus ribulose-phosphate 3-epimerase, plasmid CbbEP or CfxE SWALL:RPEP_ALCEU (SWALL:Q04539) (241 aa) fasta scores: E(): 9.3e-62, 70.71% id in 239 aa.
 0.982
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.981
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 2.5e-100, 49.9% id in 543 aa, and to Deinococcus radiodurans glucose-6-phosphate isomerase dr1742 SWALL:G6PI_DEIRA (SWALL:Q9RTL8) (541 aa) fasta scores: E(): 7.5e-120, 57.22% id in 540 aa.
  
 0.979
cbbA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.966
fbp
Similar to Alcaligenes eutrophus fructose-1,6-bisphosphatase, chromosomal CbbfC or cfxF SWALL:F16P_ALCEU (SWALL:P19911) (364 aa) fasta scores: E(): 1.2e-79, 60.41% id in 341 aa, and to Pseudomonas aeruginosa fructose-1,6-bisphosphatase Fbp or pa5110 SWALL:Q9HU73 (EMBL:AE004923) (336 aa) fasta scores: E(): 4.9e-96, 72.23% id in 335 aa.
  
 
 0.965
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
 0.957
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.953
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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