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accC accC accB accB accD accD accA accA BPSS0197 BPSS0197 fabD fabD BPSS0300 BPSS0300 BPSL1335 BPSL1335 BPSL1380 BPSL1380 acoE acoE BPSS0618 BPSS0618
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa)    
Predicted Functional Partners:
accB
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.999
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.994
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.991
BPSS0197
Putative biotin-binding protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.989
fabD
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase fabD or TfpA SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 4.4e-56, 54.72% id in 307 aa, and to Ralstonia solanacearum probable malonyl CoA-[acyl-carrier-protein] transacylase rsc1051 or rs04178 SWALL:Q8Y0J3 (EMBL:AL646062) (309 aa) fasta scores: E(): 8.2e-89, 81.31% id in 305 aa.
 
 
 0.958
BPSS0300
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 2.6e-24, 34.75% id in 305 aa, and to Bacillus subtilis PksC protein SWALL:O34825 (EMBL:Z99112) (288 aa) fasta scores: E(): 1.3e-39, 43.35% id in 286 aa.
 
 
 0.958
BPSL1335
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 2.6e-14, 29.66% id in 300 aa, and to Xanthomonas campestris malonyl CoA-ACP transacylase MdcH or xcc3615 SWALL:AAM42885 (EMBL:AE012482) (306 aa) fasta scores: E(): 3.1e-40, 48.36% id in 306 aa, and to.
 
 
 0.948
BPSL1380
Putative acetyl-CoA synthetase; Similar to Bacillus subtilis acetyl-coenzyme A synthetase AcsA SWALL:ACSA_BACSU (SWALL:P39062) (572 aa) fasta scores: E(): 5.7e-54, 34.63% id in 540 aa, and to Rhizobium loti acetyl-CoA synthetase mll6017 SWALL:Q98AG0 (EMBL:AP003008) (562 aa) fasta scores: E(): 8.3e-119, 55.51% id in 553 aa.
 
 0.921
acoE
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.921
BPSS0618
AMP-binding enzyme; Similar to Ralstonia solanacearum probable acetyl-coenzyme A synthetase rsp0651 or rs05571 SWALL:Q8XS30 (EMBL:AL646080) (567 aa) fasta scores: E(): 2.8e-165, 75.22% id in 561 aa, and to Streptomyces coelicolor putative acetyl-coenzyme A synthetase SCO6195 or SC2G5.16 SWALL:Q9Z5A7 (EMBL:AL939126) (558 aa) fasta scores: E(): 1.1e-118, 58.46% id in 561 aa.
  
 0.921
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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