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BPSL3089 BPSL3089 pepA pepA gshA-2 gshA-2 gshB gshB gshA gshA PepN PepN BPSL0416 BPSL0416 BPSL0692 BPSL0692 BPSS1288 BPSS1288 BPSL0001 BPSL0001 BPSL0671 BPSL0671
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSL3089Family M1 unassigned peptidase; Similar to Ralstonia solanacearum putative aminopeptidase transmembrane protein Rsp0532 or Rs00411 SWALL:Q8XSE4 (EMBL:AL646079) (748 aa) fasta scores: E(): 2.4e-99, 46.99% id in 749 aa, and to Mus musculus puromycin-sensitive aminopeptidase Psa SWALL:PSA_MOUSE (SWALL:Q11011) (920 aa) fasta scores: E(): 8e-34, 27.5% id in 629 aa, and to Lactobacillus helveticus aminopeptidase N PepN SWALL:AMPN_LACHE (SWALL:Q10730) (844 aa) fasta scores: E(): 1.1e-25, 30.13% id in 511 aa. (721 aa)    
Predicted Functional Partners:
pepA
Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.927
gshA-2
Similar to Escherichia coli glutamate--cysteine ligase GshA or Gsh-I SWALL:GSH1_ECOLI (SWALL:P06980) (518 aa) fasta scores: E(): 2.1e-70, 41.74% id in 515 aa, and to Pseudomonas aeruginosa glutamate--cysteine ligase pa5203 SWALL:Q9HTY6 (EMBL:AE004933) (527 aa) fasta scores: E(): 1.3e-117, 59.73% id in 529 aa; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.911
gshB
Similar to Escherichia coli glutathione synthetase GshB or Gsh-II SWALL:GSHB_ECOLI (SWALL:P04425) (316 aa) fasta scores: E(): 3.4e-53, 48.22% id in 309 aa, and to Ralstonia solanacearum glutathione synthetase rsc0345 or rs03312 SWALL:GSHB_RALSO (SWALL:P58579) (324 aa) fasta scores: E(): 2.8e-80, 68.43% id in 320 aa; Belongs to the prokaryotic GSH synthase family.
    
 0.911
gshA
Glutamate--cysteine ligase; Similar to Thiobacillus ferrooxidans glutamate--cysteine ligase GshA SWALL:Q56277 (EMBL:U81808) (436 aa) fasta scores: E(): 3.8e-78, 50.59% id in 419 aa, and to Ralstonia solanacearum hypothetical protein rsc0344 or rs03311 SWALL:Q8Y2J1 (EMBL:AL646058) (431 aa) fasta scores: E(): 2e-125, 71.86% id in 430 aa.
   
 
 0.909
PepN
Alanyl aminopeptidase; Similar to Ralstonia solanacearum probable aminopeptidase N PepN or rsc2125 or rs01479 SWALL:Q8XXI8 (EMBL:AL646068) (905 aa) fasta scores: E(): 1.1e-170, 66.11% id in 906 aa and to Escherichia coli aminopeptidase N PepN or b0932 SWALL:AMPN_ECOLI (SWALL:P04825) (869 aa) fasta scores: E(): 9.5e-101, 48.6% id in 897 aa.
  
  
 
0.908
BPSL0416
Zinc-binding dehydrogenase (fragment); PS00228 Tubulin-beta mRNA autoregulation signal.
     
 0.905
BPSL0692
Gamma-glutamyltransferase 2; Similar to Ralstonia solanacearum putative gamma-glutamyltranspeptidase protein rsc2501 or rs01094 SWALL:Q8XWH3 (EMBL:AL646070) (552 aa) fasta scores: E(): 8.6e-156, 70.73% id in 557 aa, and to Deinococcus radiodurans cephalosporin acylase dr1524 SWALL:Q9RU70 (EMBL:AE001996) (535 aa) fasta scores: E(): 5.2e-90, 50.64% id in 547 aa, and to Bacillus halodurans cephalosporin acylase bh0867 SWALL:Q9KEI5 (EMBL:AP001510) (539 aa) fasta scores: E(): 3.7e-89, 49.36% id in 547 aa; possible alternative start site at codon 4.
     
 0.905
BPSS1288
Gamma-glutamyltransferase 1; Similar to Helicobacter pylori gamma-glutamyltranspeptidase hp1118 SWALL:O25743 (EMBL:AE000618) (567 aa) fasta scores: E(): 1.3e-83, 42.43% id in 568 aa, and to Caulobacter crescentus gamma-glutamyltransferase cc0104 SWALL:Q9ABW6 (EMBL:AE005685) (583 aa) fasta scores: E(): 3.3e-132, 63.54% id in 565 aa, and to Pseudomonas aeruginosa gamma-glutamyltranspeptidase precursor Ggt or pa1338 SWALL:Q9I406 (EMBL:AE004563) (557 aa) fasta scores: E(): 3.2e-130, 63.04% id in 552 aa.
     
 0.905
BPSL0001
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
BPSL0671
Conserved hypothetical protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
  0.900
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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