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BPSL3426 BPSL3426 BPSS2246 BPSS2246 BPSL2025 BPSL2025 BPSL3427 BPSL3427 BPSS1940 BPSS1940 BPSL0807 BPSL0807 BPSS0642 BPSS0642 BPSL0039 BPSL0039 irlS2 irlS2 irlS irlS BPSL0774 BPSL0774
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL3426Similar to Rhizobium loti two-component response regulator Mll7953 SWALL:Q984L3 (EMBL:AP003013) (223 aa) fasta scores: E(): 3.7e-35, 50.66% id in 227 aa, and to Salmonella typhimurium transcriptional regulatory protein TctD or Stm2785 SWALL:TCTD_SALTY (SWALL:P22104) (224 aa) fasta scores: E(): 1.1e-29, 42.34% id in 222 aa. (230 aa)    
Predicted Functional Partners:
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
 
 0.938
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
 
 
 0.924
BPSL3427
Similar to Xanthomonas axonopodis two-component system sensor protein TctC or xac3482 SWALL:AAM38325 (EMBL:AE011996) (461 aa) fasta scores: E(): 3.6e-26, 32.27% id in 474 aa, and to Escherichia coli O157:H7 sensor protein QseC or z4378 or ecs3908/ecs3909 SWALL:QSEC_ECO57 (SWALL:Q8X524) (449 aa) fasta scores: E(): 4e-18, 29.95% id in 464 aa.
 
 
 0.918
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
 
 0.882
BPSL0807
Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 4.1e-30, 31.04% id in 451 aa, and to Ralstonia solanacearum probable transmembrane two-component sensor kinase transcription regulator protein rsp1553 or rs02109 SWALL:Q8XPT4 (EMBL:AL646085) (438 aa) fasta scores: E(): 3e-69, 50.22% id in 438 aa.
 
 
 0.832
BPSS0642
Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 4.6e-27, 32.08% id in 452 aa, and to Ralstonia solanacearum probable transmembrane two-component sensor kinase transcription regulator protein rsp1553 or rs02109 SWALL:Q8XPT4 (EMBL:AL646085) (438 aa) fasta scores: E(): 9.4e-50, 41.34% id in 445 aa.
 
 0.827
BPSL0039
Sensor kinase protein; Two-component regulatory system family, sensor kinase protein. Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 7.1e-23, 28.06% id in 449 aa, and to Rhizobium loti two-component system, sensor protein mll7952 SWALL:Q984L4 (EMBL:AP003013) (452 aa) fasta scores: E(): 3.7e-56, 41.75% id in 455 aa.
 
 
 0.826
irlS2
Metal-related two-component system, histidine kinase; Member of a two-component regulatory system.
 
 0.820
irlS
Putative transmembrane invasion-related two-component sensor protein; Member of the two-component regulatory system IrlR/IrlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance. Probably activates IrlR by phosphorylation (By similarity).
 
 0.810
BPSL0774
Similar to Ralstonia solanacearum probable transmembrane sensor histidine kinase transcription regulator protein rsc0549 or rs04917 SWALL:Q8Y1Y8 (EMBL:AL646059) (513 aa) fasta scores: E(): 3.9e-104, 58.77% id in 507 aa, and to Ralstonia solanacearum probable two-component transmembrane sensor kinase transcription regulator protein rsc1735 or rs02923 SWALL:Q8XYM3 (EMBL:AL646066) (471 aa) fasta scores: E(): 2e-49, 37.69% id in 451 aa, and to Rhizobium loti two-component system, sensor protein mll7952 SWALL:Q984L4 (EMBL:AP003013) (452 aa) fasta scores: E(): 9.4e-48, 38.28% id in 444 aa.
 
 
 0.801
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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