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fabH-2 fabH-2 fabF fabF fabD fabD BPSS0300 BPSS0300 BPSL1335 BPSL1335 fabG fabG accB accB fabZ fabZ BPSS1256 BPSS1256 FabG FabG BPSL1167 BPSL1167
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fabH-2Similar to Pseudomonas aeruginosa 3-oxoacyl-[acyl-carrier-protein] synthase III FabH or pa0999 SWALL:FABH_PSEAE (SWALL:P20582) (337 aa) fasta scores: E(): 9.7e-64, 53.84% id in 325 aa, and to Streptomyces coelicolor 3-oxoacyl-[acyl-carrier-protein] synthase sco5888 or sc3f7.08 SWALL:O54151 (EMBL:AL939125) (335 aa) fasta scores: E(): 1.3e-40, 39.93% id in 323 aa. (332 aa)    
Predicted Functional Partners:
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.992
fabD
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase fabD or TfpA SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 4.4e-56, 54.72% id in 307 aa, and to Ralstonia solanacearum probable malonyl CoA-[acyl-carrier-protein] transacylase rsc1051 or rs04178 SWALL:Q8Y0J3 (EMBL:AL646062) (309 aa) fasta scores: E(): 8.2e-89, 81.31% id in 305 aa.
 
 
 0.985
BPSS0300
Similar to Escherichia coli, and Escherichia coli O6 malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 or c1361 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 2.6e-24, 34.75% id in 305 aa, and to Bacillus subtilis PksC protein SWALL:O34825 (EMBL:Z99112) (288 aa) fasta scores: E(): 1.3e-39, 43.35% id in 286 aa.
 
 
 0.985
BPSL1335
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase FabD or TfpA or b1092 SWALL:FABD_ECOLI (SWALL:P25715) (308 aa) fasta scores: E(): 2.6e-14, 29.66% id in 300 aa, and to Xanthomonas campestris malonyl CoA-ACP transacylase MdcH or xcc3615 SWALL:AAM42885 (EMBL:AE012482) (306 aa) fasta scores: E(): 3.1e-40, 48.36% id in 306 aa, and to.
 
 
 0.977
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
  0.941
accB
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.931
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
  
 0.926
BPSS1256
Similar to Picea abies short-chain type dehydrogenase/reductase SWALL:SDR1_PICAB (SWALL:Q08632) (271 aa) fasta scores: E(): 8.8e-29, 44.84% id in 252 aa, and to Rhizobium loti probable short chain dehydrogenase mll1981 SWALL:Q98JE4 (EMBL:AP002998) (258 aa) fasta scores: E(): 9.7e-50, 59.83% id in 239 aa, and to Rhizobium meliloti putative short chain dehydrogenase/reductase protein rb0475 or smb20493 SWALL:Q92W70 (EMBL:AL603643) (244 aa) fasta scores: E(): 1.4e-48, 58.57% id in 239 aa, and to Xanthomonas axonopodis short chain dehydrogenase xac0083 SWALL:AAM34975 (EMBL:AE011631) (245 a [...]
 
 
  0.915
FabG
Putative dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 7-alpha-hydroxysteroid dehydrogenase HdhA or HsdH or b1619 or z2624 or ecs2327 SWALL:HDHA_ECOLI (SWALL:P25529) (255 aa) fasta scores: E(): 8.5e-27, 40.96% id in 249 aa, and to Ralstonia solanacearum probable toluenesulfonate zinc-independent alcohol dehydrogenase oxidoreductase protein rsc2351 or rs01195 SWALL:Q8XWW9 (EMBL:AL646069) (252 aa) fasta scores: E(): 7.7e-70, 71.42% id in 252 aa.
  
 
  0.904
BPSL1167
Putative dehydrogenase; Similar to Xanthomonas axonopodis pv. citri str. 306 oxidoreductase xac0384 SWALL:AAM35276 (EMBL:AE011664) (260 aa) fasta scores: E(): 1.7e-66, 71.53% id in 260 aa, and to Ralstonia solanacearum probable dehydrogenase/reductase oxidoreductase protein rsc2186 or rs01413 SWALL:Q8XXC9 (EMBL:AL646068) (263 aa) fasta scores: E(): 3e-61, 67.3% id in 263 aa.
  
 
  0.904
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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