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BPSS0486 BPSS0486 BPSL2229 BPSL2229 BPSS1008 BPSS1008 BPSS1269 BPSS1269 BPSL1712 BPSL1712 BPSS1181 BPSS1181 BPSS1171 BPSS1171 BPSS1197 BPSS1197 fdx fdx nuoI nuoI BPSS0299 BPSS0299
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
BPSS0486N-terminal region similar to Streptomyces atroolivaceus non-ribosomal peptide synthetase SWALL:AAN85512 (EMBL:AF484556) (1745 aa) fasta scores: E(): 2.8e-67, 36.51% id in 838 aa, and C-terminal region similar to Pseudomonas aeruginosa probable acyl-CoA dehydrogenase pa1631 SWALL:Q9I391 (EMBL:AE004590) (384 aa) fasta scores: E(): 2e-23, 32.13% id in 361 aa. (1291 aa)    
Predicted Functional Partners:
BPSL2229
Similar to Pseudomonas putida siderophore non-ribosomal peptide synthetase PpsD SWALL:Q9AKS6 (EMBL:AJ310530) (2246 aa) fasta scores: E(): 4.8e-102, 28.54% id in 2659 aa, and to the C-terminal region of Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-94, 27.02% id in 3648 aa.
0.999
BPSS1008
Putative polyketide synthase; N-terminal region is similar to the the N-terminal region of Bacillus subtilis putative polyketide synthase PksK SWALL:PKSK_BACSU (SWALL:P40803) (4447 aa) fasta scores: E(): 1.1e-167, 38.79% id in 3439 aa. Internal region is similar to an internal region of Pseudomonas fluorescens MmpIV protein SWALL:Q8RL72 (EMBL:AF318063) (6521 aa) fasta scores: E(): 2.8e-41, 32.83% id in 4069 aa.
 
0.999
BPSS1269
Putative peptide synthase/polyketide synthase; Similar to C-terminus of Aphanizomenon ovalisporum peptide synthetase AoaB SWALL:AAM33468 (EMBL:AF395828) (1869 aa) fasta scores: E(): 5.4e-125, 35.68% id in 1841 aa, and to C-terminus of Stigmatella aurantiaca MtaD SWALL:Q9RFK8 (EMBL:AF188287) (3291 aa) fasta scores: E(): 7.3e-124, 29.54% id in 3368 aa.
0.999
BPSL1712
Putative non-ribosomal antibiotic-related peptide synthase; Similar to Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-105, 31.93% id in 6198 aa, and to all the domains of Bacillus brevis tyrocidine synthetase III TycC SWALL:TYCC_BACBR (SWALL:O30409) blast scores: E(): 0.0, score: 4799 27% id. Note: Taking into consideration the blastp similarities and all the similarities to the domains in Bacillus brevis TycC, it could be proposed that BSPL1712 possibly incorporates six amino acids (Asn, Gln, Tyr, Val, Orn and Leu) into [...]
 
0.998
BPSS1181
Putative surfactin/non-ribosomally encoded peptide/polyketide synthase; Similar to Streptomyces pristinaespiralis pristinamycin I synthase I SnbC SWALL:Q54959 (EMBL:X98690) (2591 aa) fasta scores: E(): 6.9e-60, 41.81% id in 507 aa, and to Anabaena sp. hypothetical protein All1695 SWALL:Q8YWC0 (EMBL:AP003586) (1449 aa) fasta scores: E(): 4.5e-62, 41.42% id in 507 aa; Belongs to the ATP-dependent AMP-binding enzyme family.
 0.996
BPSS1171
Putative non-ribosomal peptide synthase/polyketide synthase; Similar to Anabaena sp. 90 peptide synthetase AdpA SWALL:Q9K5M2 (EMBL:AJ269505) (2258 aa) fasta scores: E(): 2.2e-72, 29.05% id in 1084 aa, and to Ralstonia solanacearum probable peptide synthetase protein rsp0642 or rs05859 SWALL:Q8XS39 (EMBL:AL646079) (5953 aa) fasta scores: E(): 1e-66, 33.39% id in 1069 aa, and to Myxococcus xanthus saframycin mx1 synthetase B SafB SWALL:Q50857 (EMBL:U24657) (1770 aa) fasta scores: E(): 4.3e-61, 39.62% id in 593 aa.
 0.992
BPSS1197
Putative non-ribosomal peptide synthase; Similar to central portion of Ralstonia solanacearum probable peptide synthetase protein rsp0641 or rs05860 SWALL:Q8XS40 (EMBL:AL646079) (6889 aa) fasta scores: E(): 1.4e-124, 33.62% id in 3396 aa, and to N-terminus of Stigmatella aurantiaca StiC protein SWALL:Q8RJY4 (EMBL:AJ421825) (1885 aa) fasta scores: E(): 3.5e-95, 41.69% id in 933 aa, and to N-terminus of Stigmatella aurantiaca StiB protein SWALL:Q8RJY5 (EMBL:AJ421825) (1585 aa) fasta scores: E(): 1.3e-91, 36.35% id in 1268 aa.
 0.991
fdx
Ferredoxin; Similar to Chromatium vinosum ferredoxin Fdx SWALL:FER_CHRVI (SWALL:P00208) (82 aa) fasta scores: E(): 2.3e-19, 72% id in 75 aa, and to Ralstonia solanacearum probable ferredoxin protein rsc0391 or rs03359 SWALL:Q8Y2E5 (EMBL:AL646059) (82 aa) fasta scores: E(): 6.2e-26, 85.36% id in 82 aa.
  
 0.990
nuoI
Putative NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 0.990
BPSS0299
Putative fatty-acid CoA ligase; Similar to the N-terminal region of Streptomyces coelicolor polyketide synthase sco5892 or sc3f7.12 SWALL:O54155 (EMBL:AL939125) (2297 aa) fasta scores: E(): 2.6e-69, 41.73% id in 587 aa, and to the full length of Mycobacterium tuberculosis putative fatty-acid--CoA ligase rv1521 or mt1572 or mtcy19g5.07 SWALL:FD25_MYCTU (SWALL:Q50586) (583 aa) fasta scores: E(): 5.3e-56, 36.65% id in 592 aa.
 
0.990
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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