STRINGSTRING
BPSS0563 BPSS0563 BPSS0564 BPSS0564 BPSS2305 BPSS2305 BPSS0827 BPSS0827 BPSS0666 BPSS0666 metH2 metH2 BPSL1135 BPSL1135 BPSS0580 BPSS0580 lipA1 lipA1 lipA2 lipA2 BPSS0974 BPSS0974
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS0563Aminopeptidase; Similar to the N-terminal region of Vibrio proteolyticus bacterial leucyl aminopeptidase precursor SWALL:AMPX_VIBPR (SWALL:Q01693) (504 aa) fasta scores: E(): 1.8e-62, 45.27% id in 402 aa, and to the full length Aeromonas punctata aminopeptidase ApaC SWALL:O82996 (EMBL:AB015725) (393 aa) fasta scores: E(): 2.6e-61, 46.63% id in 401 aa. (408 aa)    
Predicted Functional Partners:
BPSS0564
Putative thermolysin metallopeptidase; Similar to Bacillus stearothermophilus thermolysin precursor NprT SWALL:THER_BACST (SWALL:P06874) (548 aa) fasta scores: E(): 0.00076, 23.78% id in 597 aa, and to Alicyclobacillus acidocaldarius thermolysin precursor SWALL:Q43880 (EMBL:U07824) (546 aa) fasta scores: E(): 2.5e-05, 24.32% id in 592 aa.
 
  
 0.760
BPSS2305
Putative lipoprotein; Similar to Xanthomonas axonopodis disulphide-isomerase xac3878 SWALL:AAM38720 (EMBL:AE012037) (526 aa) fasta scores: E(): 3.7e-46, 36.06% id in 524 aa, and to Xanthomonas campestris disulphide-isomerase xcc3823 SWALL:AAM43059 (EMBL:AE012503) (525 aa) fasta scores: E(): 4.2e-41, 34.04% id in 517 aa.
  
     0.649
BPSS0827
Subfamily M9A unassigned peptidase; C-terminus is similar to the C-terminal region of Vibrio parahaemolyticus microbial collagenase precursor PrtVp SWALL:COLA_VIBPA (SWALL:Q56696) (587 aa) fasta scores: E(): 3.4e-43, 31.36% id in 542 aa. Similar to the N-terminal region of Streptomyces coelicolor SC10A5.17 protein SCO5912 or SC10A5.17 SWALL:O54108 (EMBL:AL939125) (865 aa) fasta scores: E(): 2.8e-63, 35.88% id in 627 aa. Similar to BPSS0666, 81.329% identity (81.458% ungapped) in 632 aa overlap.
  
     0.636
BPSS0666
Putative collagenase; Subfamily M9A unassigned peptidase. C-terminal region is similar to an internal region of Vibrio alginolyticus microbial collagenase precursor SWALL:COLA_VIBAL (SWALL:P43154) (814 aa) fasta scores: E(): 1.8e-54, 32.52% id in 578 aa, and to the C-terminal region of Vibrio parahaemolyticus microbial collagenase precursor PrtVp SWALL:COLA_VIBPA (SWALL:Q56696) (587 aa) fasta scores: E(): 9.3e-48, 33.21% id in 545 aa. Similar to BPSS0827, 81.329% identity (81.458% ungapped) in 632 aa overlap.
  
     0.635
metH2
Similar to Ralstonia solanacearum probable 5-methyltetrahydrofolate--homocysteine methyltransferase rsc0295 or rs03262 SWALL:Q8Y2P0 (EMBL:AL646058) (346 aa) fasta scores: E(): 2.9e-107, 80.29% id in 345 aa, and to the N-terminal region Escherichia coli 5-methyltetrahydrofolate--homocysteine methyltransferase MetH SWALL:METH_ECOLI (SWALL:P13009) (1226 aa) fasta scores: E(): 3.2e-72, 59.07% id in 325 aa. BPSL0385 and BPSL03856 are similar to the N- and C-terminal regions of many 5-methyltetrahydrofolate--homocysteine methyltransferases. In some organisms these two domains are also found [...]
     
 0.513
BPSL1135
Hypothetical protein; No significant database matches.
  
    0.487
BPSS0580
Subfamily M23A unassigned peptidase; N-terinal region is similar to the C-terminal region of Pseudomonas aeruginosa protease LasA SWALL:LASA_PSEAE (SWALL:P14789) (418 aa) fasta scores: E(): 6.2e-10, 29.22% id in 308 aa, and to Achromobacter lyticus beta-lytic metalloendopeptidase precursor SWALL:PRLB_ACHLY (SWALL:P27458) (374 aa) fasta scores: E(): 1.2e-08, 28.85% id in 305 aa.
  
  
 0.478
lipA1
Lipase precursor; Similar to Burkholderia cepacia lipase precursor LipA SWALL:LIP_BURCE (SWALL:P22088) (364 aa) fasta scores: E(): 7.1e-111, 84.34% id in 364 aa, and to Pseudomonas sp. Lipase precursor Lip SWALL:LIP_PSES5 (SWALL:P25275) (364 aa) fasta scores: E(): 4.2e-110, 83.79% id in 364 aa.
  
     0.422
lipA2
Lipase precursor; Similar to Burkholderia cepacia lipase precursor LipA SWALL:LIP_BURCE (SWALL:P22088) (364 aa) fasta scores: E(): 2.1e-83, 65.65% id in 364 aa, and to Pseudomonas sp. lipase precursor Lip SWALL:LIP_PSES5 (SWALL:P25275) (364 aa) fasta scores: E(): 5.4e-84, 66.2% id in 364 aa. Similar to BPSS1741, 67.397% identity (70.690% ungapped) in 365 aa overlap.
  
     0.422
BPSS0974
Subfamily S8A unassigned peptidase; No significant database matches to the full length CDS. C-teminal region is similar to an internal region of Bacteroides nodosus extracellular basic protease precursor BprV or Bpr SWALL:BPRV_BACNO (SWALL:P42779) (603 aa) fasta scores: E(): 8.9e-41, 39.94% id in 393 aa. C-terminal region is similar to Burkholderia pseudomallei serine metalloprotease precursor SWALL:Q9F881 (EMBL:AF254803) (500 aa) fasta scores: E(): 1.6e-71, 52.4% id in 500 aa. C-terminal region is similar to BPSS1993, 52.400% identity (54.132% ungapped) in 500 aa overlap.
  
   
 0.420
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (28%) [HD]