STRINGSTRING
BPSS0618 BPSS0618 mmsA mmsA aceB aceB BPSS1955 BPSS1955 BPSL0890 BPSL0890 prpC prpC gltA gltA BPSL0062 BPSL0062 BPSL0371 BPSL0371 BPSL1426 BPSL1426 phbA phbA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS0618AMP-binding enzyme; Similar to Ralstonia solanacearum probable acetyl-coenzyme A synthetase rsp0651 or rs05571 SWALL:Q8XS30 (EMBL:AL646080) (567 aa) fasta scores: E(): 2.8e-165, 75.22% id in 561 aa, and to Streptomyces coelicolor putative acetyl-coenzyme A synthetase SCO6195 or SC2G5.16 SWALL:Q9Z5A7 (EMBL:AL939126) (558 aa) fasta scores: E(): 1.1e-118, 58.46% id in 561 aa. (567 aa)    
Predicted Functional Partners:
mmsA
Similar to Pseudomonas aeruginosa methylmalonate-semialdehyde dehydrogenase [acylating] MmsA SWALL:MMSA_PSEAE (SWALL:P28810) (496 aa) fasta scores: E(): 6.6e-114, 58.46% id in 496 aa, and to Ralstonia solanacearum probable methylmalonate-semialdehyde dehydrogenase oxidoreductase protein rsp0650 or rs05572 SWALL:Q8XS31 (EMBL:AL646080) (515 aa) fasta scores: E(): 3.2e-161, 80.86% id in 507 aa.
  
 0.968
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 1.9e-103, 50.84% id in 533 aa, and to Ralstonia solanacearum probable malate synthase A rsc1363 or rs04645 SWALL:Q8XZN2 (EMBL:AL646064) (529 aa) fasta scores: E(): 1.5e-177, 79.84% id in 531 aa.
   
 0.953
BPSS1955
Putative phosphate acetyltransferase/enoyl-CoA hydratase fusion protein; N-terminal region similar to Pseudomonas aeruginosa (R)-specific enoyl-CoA hydratase PhaJ1 or pa3302 SWALL:Q9LBK2 (EMBL:AB040025) (156 aa) fasta scores: E(): 1.1e-17, 44.44% id in 153 aa, and C-terminal region to Rhizobium meliloti phosphate acetyltransferase Pta SWALL:PTA_RHIME (SWALL:Q9X448) (316 aa) fasta scores: E(): 5.4e-55, 57.37% id in 305 aa.
  
 
 0.948
BPSL0890
Putative citrate synthase; C-terminal region is similar to Agrobacterium tumefaciens citrate synthase CisZ or atu4851 or agr_l_71 SWALL:Q8U6F6 (EMBL:AE009414) (335 aa) fasta scores: E(): 6.7e-14, 42.68% id in 335 aa, and to Staphylococcus aureus citrate synthase II CitZ SWALL:Q99TG7 (EMBL:AP003363) (373 aa) fasta scores: E(): 4.7e-13, 27.36% id in 391 aa. Possible alternative translational start site.
  
 0.947
prpC
Similar to Escherichia coli 2-methylcitrate synthase PrpC or b0333 SWALL:PRPC_ECOLI (SWALL:P31660) (389 aa) fasta scores: E(): 3.5e-119, 78.61% id in 374 aa, and to Burkholderia sacchari 2-methylcitrate synthase PrpC SWALL:Q8VPS9 (EMBL:AY033092) (388 aa) fasta scores: E(): 1.2e-133, 86.15% id in 390 aa.
  
 0.947
gltA
Citrate synthase; Similar to Rhizobium meliloti citrate synthase GltA or r01509 or smc02087 SWALL:CISY_RHIME (SWALL:O33915) (429 aa) fasta scores: E(): 1.4e-128, 70.23% id in 430 aa, and to Ralstonia solanacearum probable citrate synthase protein rsc1991 or rs03559 SWALL:Q8XXX2 (EMBL:AL646067) (433 aa) fasta scores: E(): 6.9e-149, 82.44% id in 433 aa.
  
 0.947
BPSL0062
Similar to Pseudomonas putida beta-ketoadipyl CoA thiolase PcaF SWALL:PCAF_PSEPU (SWALL:Q51956) (400 aa) fasta scores: E(): 8e-34, 41.8% id in 421 aa, and to Caulobacter crescentus fatty oxidation complex, beta subunit, putative CC0077 SWALL:Q9ABZ3 (EMBL:AE005682) (401 aa) fasta scores: E(): 5.5e-95, 71% id in 400 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
BPSL0371
Similar to Alcaligenes eutrophus acetyl-CoA acetyltransferase PhbA SWALL:THIL_ALCEU (SWALL:P14611) (393 aa) fasta scores: E(): 1.5e-65, 48.84% id in 389 aa, and to Ralstonia solanacearum probable acetyl-CoA acetyltransferase rsc0276 or rs03243 SWALL:Q8Y2Q9 (EMBL:AL646058) (393 aa) fasta scores: E(): 6.7e-109, 74.42% id in 391 aa. Similar to BPSL1535, 50.643% identity (51.036% ungapped) in 389 aa overlap; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
BPSL1426
Putative thiolase; Similar to Ralstonia solanacearum probable acetyl-CoA acetyltransferase protein rsc1761 or rs02948 SWALL:Q8XYJ7 (EMBL:AL646066) (392 aa) fasta scores: E(): 1.6e-124, 85.2% id in 392 aa, and to Pseudomonas aeruginosa probable acyl-CoA thiolase pa3454 SWALL:Q9HYF2 (EMBL:AE004766) (394 aa) fasta scores: E(): 4.5e-74, 53.69% id in 393 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
phbA
Similar to Alcaligenes eutrophus acetyl-CoA acetyltransferase PhbA SWALL:THIL_ALCEU (SWALL:P14611) (393 aa) fasta scores: E(): 4.9e-117, 85.96% id in 392 aa, and to Burkholderia sp. DSMZ 9242 PhaA SWALL:Q9RB81 (EMBL:AF153086) (393 aa) fasta scores: E(): 9.4e-127, 92.36% id in 393 aa. Note: Also similar to BPSL1540 (418 aa) fasta scores: E(): 6e-62, 52.806% identity in 392 aa overlap and to BPSL0371 (398 aa) fasta scores: E(): 7.2e-59, 50.643% identity in 389 aa overlap; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.931
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (26%) [HD]