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BPSS0688 BPSS0688 BPSS0687 BPSS0687 BPSL2025 BPSL2025 BPSS2246 BPSS2246 BPSS1940 BPSS1940 BPSS0631 BPSS0631 irlS2 irlS2 irlS irlS BPSS0642 BPSS0642 BPSS0706 BPSS0706 BPSL0039 BPSL0039
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
BPSS0688Response regulator protein; Similar to Escherichia coli transcriptional regulatory protein RstA or UrpT SWALL:RSTA_ECOLI (SWALL:P52108) (242 aa) fasta scores: E(): 1.3e-32, 42.61% id in 237 aa, and to Ralstonia solanacearum probable response regulator transcription regulator protein rsc3064 or rs00508 SWALL:Q8XUW9 (EMBL:AL646073) (243 aa) fasta scores: E(): 5.1e-78, 83.12% id in 243 aa. (240 aa)    
Predicted Functional Partners:
BPSS0687
Similar to Escherichia coli sensor protein RstB or UspT SWALL:RSTB_ECOLI (SWALL:P18392) (433 aa) fasta scores: E(): 3.3e-37, 33.63% id in 437 aa, and to Ralstonia solanacearum probable transmembrane sensor histidine kinase transcription regulator protein rsc3063 or rs00507 SWALL:Q8XUX0 (EMBL:AL646073) (433 aa) fasta scores: E(): 1.9e-84, 55.88% id in 433 aa.
 
 
 0.979
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
 
 
 0.928
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
 
 
0.875
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
 
 
 0.863
BPSS0631
Sensor protein; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Escherichia coli sensor protein CpxA or EcfB or Ssd or Eup SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 9.9e-15, 31.93% id in 238 aa, and to Pseudomonas aeruginosa probable two-component sensor pa1798 SWALL:Q9I2U4 (EMBL:AE004606) (428 aa) fasta scores: E(): 1.7e-33, 39.17% id in 291 aa. Possible alternative translational start site.
 
 
 0.831
irlS2
Metal-related two-component system, histidine kinase; Member of a two-component regulatory system.
 
 0.810
irlS
Putative transmembrane invasion-related two-component sensor protein; Member of the two-component regulatory system IrlR/IrlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance. Probably activates IrlR by phosphorylation (By similarity).
 
 0.807
BPSS0642
Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 4.6e-27, 32.08% id in 452 aa, and to Ralstonia solanacearum probable transmembrane two-component sensor kinase transcription regulator protein rsp1553 or rs02109 SWALL:Q8XPT4 (EMBL:AL646085) (438 aa) fasta scores: E(): 9.4e-50, 41.34% id in 445 aa.
 
 
 0.805
BPSS0706
Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 1.5e-29, 33.11% id in 468 aa, and to Ralstonia solanacearum probable two-component transmembrane sensor kinase transcription regulator protein rsc1735 or rs02923 SWALL:Q8XYM3 (EMBL:AL646066) (471 aa) fasta scores: E(): 2.4e-87, 59.64% id in 456 aa. CDS is extended at the C-terminus in comparison to orthologues.
 
 
 0.792
BPSL0039
Sensor kinase protein; Two-component regulatory system family, sensor kinase protein. Similar to Escherichia coli sensor protein QseC SWALL:QSEC_ECOLI (SWALL:P40719) (449 aa) fasta scores: E(): 7.1e-23, 28.06% id in 449 aa, and to Rhizobium loti two-component system, sensor protein mll7952 SWALL:Q984L4 (EMBL:AP003013) (452 aa) fasta scores: E(): 3.7e-56, 41.75% id in 455 aa.
 
 
 0.791
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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