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BPSS0710 BPSS0710 BPSS1000 BPSS1000 BPSL0391 BPSL0391 BPSL2025 BPSL2025 BPSS1940 BPSS1940 BPSS2246 BPSS2246 BPSS2345 BPSS2345 BPSS1008 BPSS1008 BPSL2229 BPSL2229 BPSS1269 BPSS1269 BPSS0486 BPSS0486
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
BPSS0710enoyl-CoA hydratase/isomerase family protein; Similar to Paracoccus pantotrophus enoyl coenzyme A hydratase-like protein SWALL:Q9EYZ0 (EMBL:AF308446) (266 aa) fasta scores: E(): 3e-50, 54.47% id in 268 aa, and to Rhizobium loti enoyl-CoA hydratase mlr8461 SWALL:Q982W6 (EMBL:AP003014) (273 aa) fasta scores: E(): 7.2e-43, 52.36% id in 254 aa. (261 aa)    
Predicted Functional Partners:
BPSS1000
Similar to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI pksI SWALL:PKSI_BACSU (SWALL:P40802) (249 aa) fasta scores: E(): 2.6e-41, 62.55% id in 243 aa, and to Pseudomonas fluorescens MupK SWALL:Q8RL61 (EMBL:AF318063) (247 aa) fasta scores: E(): 1.3e-37, 58.13% id in 246 aa, and to Yersinia pestis putative enoyl-CoA hydratase ypo1459 SWALL:Q8ZG56 (EMBL:AJ414148) (253 aa) fasta scores: E(): 7.7e-21, 35.04% id in 234 aa.
 
   0.818
BPSL0391
enoyl-CoA hydratase/isomerase family protein; Similar to Escherichia coli probable enoyl-CoA hydratase PaaG SWALL:PAAG_ECOLI (SWALL:P77467) (262 aa) fasta scores: E(): 1e-14, 30.8% id in 237 aa, and to Ralstonia solanacearum probable enoyl-CoA hydratase protein rsc0304 or rs03271 SWALL:Q8Y2N1 (EMBL:AL646058) (272 aa) fasta scores: E(): 2e-75, 74.26% id in 272 aa; Belongs to the enoyl-CoA hydratase/isomerase family.
 
   0.776
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
   
 
 0.759
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
   
 
 0.759
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
   
 
 0.759
BPSS2345
Sensory kinase protein; No significant database matches to the full length CDS. C-terminus is similar to the C-terminal regions of Brucella melitensis sensory transduction protein kinase bmei0947 SWALL:Q8YH57 (EMBL:AE009535) (767 aa) fasta scores: E(): 1.7e-39, 35.64% id in 418 aa, and Caulobacter crescentus sensory box histidine kinase/response regulator cc2874 SWALL:Q9A4G0 (EMBL:AE005952) (794 aa) fasta scores: E(): 1.6e-34, 33.82% id in 541 aa. Possible alternative translational start site.
   
 
 0.750
BPSS1008
Putative polyketide synthase; N-terminal region is similar to the the N-terminal region of Bacillus subtilis putative polyketide synthase PksK SWALL:PKSK_BACSU (SWALL:P40803) (4447 aa) fasta scores: E(): 1.1e-167, 38.79% id in 3439 aa. Internal region is similar to an internal region of Pseudomonas fluorescens MmpIV protein SWALL:Q8RL72 (EMBL:AF318063) (6521 aa) fasta scores: E(): 2.8e-41, 32.83% id in 4069 aa.
  
 0.718
BPSL2229
Similar to Pseudomonas putida siderophore non-ribosomal peptide synthetase PpsD SWALL:Q9AKS6 (EMBL:AJ310530) (2246 aa) fasta scores: E(): 4.8e-102, 28.54% id in 2659 aa, and to the C-terminal region of Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-94, 27.02% id in 3648 aa.
  
 
 0.705
BPSS1269
Putative peptide synthase/polyketide synthase; Similar to C-terminus of Aphanizomenon ovalisporum peptide synthetase AoaB SWALL:AAM33468 (EMBL:AF395828) (1869 aa) fasta scores: E(): 5.4e-125, 35.68% id in 1841 aa, and to C-terminus of Stigmatella aurantiaca MtaD SWALL:Q9RFK8 (EMBL:AF188287) (3291 aa) fasta scores: E(): 7.3e-124, 29.54% id in 3368 aa.
  
 
 0.705
BPSS0486
N-terminal region similar to Streptomyces atroolivaceus non-ribosomal peptide synthetase SWALL:AAN85512 (EMBL:AF484556) (1745 aa) fasta scores: E(): 2.8e-67, 36.51% id in 838 aa, and C-terminal region similar to Pseudomonas aeruginosa probable acyl-CoA dehydrogenase pa1631 SWALL:Q9I391 (EMBL:AE004590) (384 aa) fasta scores: E(): 2e-23, 32.13% id in 361 aa.
  
 0.664
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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