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BPSS1466 BPSS1466 gabT gabT acoE acoE BPSS0514 BPSS0514 BPSL1380 BPSL1380 BPSS0618 BPSS0618 flhA flhA BPSL1550 BPSL1550 ackA ackA speB-2 speB-2 BPSL0063 BPSL0063
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
BPSS1466Putative aldehyde dehydrogenase family protein; Similar to Streptomyces clavuligerus semialdehyde dehydrogenase Pcd SWALL:O85725 (EMBL:AF073895) (512 aa) fasta scores: E(): 2e-120, 66.05% id in 492 aa, and to Ralstonia solanacearum putative transmembrane aldehyde dehydrogenase oxidoreductase protein rsp1591 or rs02148 SWALL:Q8XPP7 (EMBL:AL646085) (504 aa) fasta scores: E(): 9.4e-134, 69.84% id in 504 aa, and to Rhizobium loti aldehyde dehydrogenase mll2867 SWALL:Q98HH4 (EMBL:AP003000) (504 aa) fasta scores: E(): 4.1e-132, 68.93% id in 499 aa. (503 aa)    
Predicted Functional Partners:
gabT
Similar to Escherichia coli 4-aminobutyrate aminotransferase GabT or b2662 SWALL:GABT_ECOLI (SWALL:P22256) (426 aa) fasta scores: E(): 4.8e-79, 54.24% id in 424 aa, and to Ralstonia solanacearum probable 4-aminobutyrate aminotransferase protein rsc0029 or rs01852 SWALL:Q8Y3F1 (EMBL:AL646057) (426 aa) fasta scores: E(): 1.5e-108, 71.29% id in 418 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.950
acoE
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.940
BPSS0514
acetyl-CoA hydrolase/transferase; Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 2e-97, 51.73% id in 520 aa, and to Xanthomonas campestris coa tranferase xcc3588 SWALL:Q8P4W8 (EMBL:AE012479) (504 aa) fasta scores: E(): 1.2e-133, 68.52% id in 502 aa. Possible alternative translational start sites.
  
 
 0.932
BPSL1380
Putative acetyl-CoA synthetase; Similar to Bacillus subtilis acetyl-coenzyme A synthetase AcsA SWALL:ACSA_BACSU (SWALL:P39062) (572 aa) fasta scores: E(): 5.7e-54, 34.63% id in 540 aa, and to Rhizobium loti acetyl-CoA synthetase mll6017 SWALL:Q98AG0 (EMBL:AP003008) (562 aa) fasta scores: E(): 8.3e-119, 55.51% id in 553 aa.
   
 0.926
BPSS0618
AMP-binding enzyme; Similar to Ralstonia solanacearum probable acetyl-coenzyme A synthetase rsp0651 or rs05571 SWALL:Q8XS30 (EMBL:AL646080) (567 aa) fasta scores: E(): 2.8e-165, 75.22% id in 561 aa, and to Streptomyces coelicolor putative acetyl-coenzyme A synthetase SCO6195 or SC2G5.16 SWALL:Q9Z5A7 (EMBL:AL939126) (558 aa) fasta scores: E(): 1.1e-118, 58.46% id in 561 aa.
   
 0.926
flhA
Similar to Paracoccus denitrificans glutathione-dependent formaldehyde dehydrogenase FlhA SWALL:FADH_PARDE (SWALL:P45382) (375 aa) fasta scores: E(): 1e-108, 75.2% id in 375 aa, and to Ralstonia solanacearum probable bifunctional: glutathione-dependent formaldehyde dehydrogenase and alcohol dehydrogenase class III oxidoreductase protein AdhC1 or rsp0069 or rs02044 SWALL:Q8XTN7 (EMBL:AL646076) (368 aa) fasta scores: E(): 4e-128, 88.04% id in 368 aa; Upstream repeat region (ggcgc)3; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.915
BPSL1550
Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SWALL:DHAB_BACSU (SWALL:P71016) (490 aa) fasta scores: E(): 1.9e-59, 40.33% id in 476 aa, and to Ralstonia solanacearum putative betaine aldehyde dehydrogenase rsc1456 or rs03851 SWALL:Q8XZE5 (EMBL:AL646064) (478 aa) fasta scores: E(): 1.1e-127, 71.3% id in 474 aa.
  
  
 
0.915
ackA
Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.915
speB-2
Agmatinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri agmatinase SpeB or b2937 or z4281 or ecs3812 or sf2927 SWALL:SPEB_ECOLI (SWALL:P16936) (306 aa) fasta scores: E(): 1.3e-23, 42.17% id in 294 aa, and to Pseudomonas aeruginosa agmatinase SpeB2 or pa1421 SWALL:Q9I3S3 (EMBL:AE004571) (319 aa) fasta scores: E(): 1.3e-89, 71.47% id in 319 aa; Belongs to the arginase family.
  
 0.913
BPSL0063
Similar to Pseudomonas fragi fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase; 3- hydroxybutyryl-CoA epimerase] FaoA SWALL:FAOB_PSEFR (SWALL:P28793) (715 aa) fasta scores: E(): 5e-65, 36.06% id in 721 aa, and to Caulobacter crescentus fatty oxidation complex, alpha subunit CC0076 SWALL:Q9ABZ4 (EMBL:AE005681) (709 aa) fasta scores: E(): 8.9e-130, 55.26% id in 684 aa.
  
 0.912
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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