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BPSS1495 BPSS1495 BPSS2246 BPSS2246 BPSL2025 BPSL2025 BPSS1940 BPSS1940 BPSS1876 BPSS1876 BPSS1871 BPSS1871 BPSS1494 BPSS1494 BPSS1360 BPSS1360 BPSL0732 BPSL0732 BPSL0703 BPSL0703 BPSS1358 BPSS1358
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BPSS1495Putative two-component regulator sensor kinase; Similar to Pseudomonas aeruginosa probable two-component sensor pa2571 SWALL:Q9I0R5 (EMBL:AE004685) (470 aa) fasta scores: E(): 4.9e-11, 26.43% id in 401 aa, and to Chlorobium tepidum sensor histidine kinase/response regulator ct1396 SWALL:AAM72624 (EMBL:AE012897) (808 aa) fasta scores: E(): 2.1e-06, 29.09% id in 409 aa, and to Anabaena sp. two-component hybrid sensor and regulator alr1968 SWALL:Q8YVK7 (EMBL:AP003587) (759 aa) fasta scores: E(): 2.3e-06, 29.8% id in 312 aa. (614 aa)    
Predicted Functional Partners:
BPSS2246
Putative sensor kinase/response regulator fusion protein; Similar to Anabaena sp. two-component hybrid sensor and regulator alr3442 SWALL:Q8YRK4 (EMBL:AP003593) (865 aa) fasta scores: E(): 1.3e-49, 30.58% id in 680 aa, and to Ralstonia solanacearum probable composite two-component regulatory rsp1676 or rs02235 SWALL:Q8XPG5 (EMBL:AL646086) (796 aa) fasta scores: E(): 1e-42, 32.65% id in 640 aa.
 
 
 0.995
BPSL2025
Putative two component regulatory system, sensor kinase; Similar to the C-terminal region of Escherichia coli sensor protein RcsC or b2218 SWALL:RCSC_ECOLI (SWALL:P14376) (949 aa) fasta scores: E(): 2e-37, 32.94% id in 513 aa, and of Salmonella typhi sensor protein RcsC or sty2496 SWALL:RCSC_SALTI (SWALL:Q56128) (948 aa) fasta scores: E(): 1.2e-35, 32.82% id in 521 aa.
 
 
 0.994
BPSS1940
Similar to Caulobacter crescentus sensory box histidine kinase/response regulator cc3225 SWALL:Q9A3H9 (EMBL:AE005986) (731 aa) fasta scores: E(): 9.5e-57, 35.17% id in 688 aa, and to Pseudomonas putida sensor histidine kinase/response regulator pp3651 SWALL:AAN69251 (EMBL:AE016787) (727 aa) fasta scores: E(): 6.1e-51, 33.19% id in 729 aa.
 
 
0.991
BPSS1876
Putative sensor kinase/response regulator fusion protein; N-terminal region similar to Pseudomonas aeruginosa probable two-component response regulator pa3702 SWALL:Q9HXT9 (EMBL:AE004789) (347 aa) fasta scores: E(): 3.7e-29, 64.92% id in 134 aa, C-terminal region to Caulobacter crescentus sensory box histidine kinase, putative cc3327 SWALL:Q9A377 (EMBL:AE005994) (761 aa) fasta scores: E(): 9.5e-22, 37.61% id in 226 aa, and in full length to Mycobacterium leprae sensor-like histidine kinase SenX3 or ml2440 or b2168_c3_247 SWALL:SEX3_MYCLE (SWALL:P54883) (443 aa) fasta scores: E(): 1.9e- [...]
 
 
 0.983
BPSS1871
Putative chemotaxis-related histidine kinase protein; Similar to Thermotoga maritima chemotaxis protein CheA or tm0702 SWALL:CHEA_THEMA (SWALL:Q56310) (671 aa) fasta scores: E(): 2.2e-33, 27.4% id in 708 aa, and to Rhizobium loti chemotaxis histidine kinase mll9511 SWALL:Q98PD0 (EMBL:AP003017) (757 aa) fasta scores: E(): 1.1e-104, 49.07% id in 864 aa.
 
 
 0.961
BPSS1494
Putative two-component response regulator protein; Similar to Rhizobium sp LcrB protein SWALL:Q53167 (EMBL:M38698) (238 aa) fasta scores: E(): 9.9e-34, 43.16% id in 234 aa, and to Agrobacterium tumefaciens Tiorf152 protein SWALL:BAA87777 (EMBL:AB016260) (253 aa) fasta scores: E(): 3.5e-32, 41% id in 239 aa, and to Agrobacterium tumefaciens regulatory protein VirG or atu6178 or agr_pti_15 SWALL:VIRG_AGRT5 (SWALL:P07545) (253 aa) fasta scores: E(): 3.5e-32, 41% id in 239 aa.
 
 
 0.959
BPSS1360
Putative two-component sensor kinase protein; C-terminus is similar to the C-terminal regions of Anabaena sp. cyanobacterial phytochrome A AphA or ALR3157 SWALL:PHYA_ANASP (SWALL:Q9LCC2) (765 aa) fasta scores: E(): 3.5e-45, 54.78% id in 261 aa, and to Methanosarcina acetivorans sensory transduction histidine kinase MA1270 SWALL:Q8TRB0 (EMBL:AE010795) (1456 aa) fasta scores: E(): 4.8e-62, 41.14% id in 508 aa.
 
 
0.939
BPSL0732
Putative two-component regulator histidine sensor kinase; Similar to Rhodobacter sphaeroides DMSO/TMAO-sensor kinase dorS SWALL:O30740 (EMBL:AF016236) (815 aa) fasta scores: E(): 4.6e-25, 33.24% id in 385 aa, and to Caulobacter crescentus sensor histidine kinase / response regulator cc0723 SWALL:Q9AA83 (EMBL:AE005747) (591 aa) fasta scores: E(): 1.6e-27, 30.34% id in 412 aa, and to Xanthomonas campestris two-component system sensor protein xcc2360 SWALL:AAM41638 (EMBL:AE012344) (1364 aa) fasta scores: E(): 3.7e-26, 29.7% id in 404 aa.
 
 
0.917
BPSL0703
Putative two-component sensor histidine kinase; Similar to Xanthomonas campestris histidine kinase xcc1957 SWALL:AAM41246 (EMBL:AE012299) (408 aa) fasta scores: E(): 1.1e-42, 50.16% id in 297 aa, and to Xanthomonas axonopodis histidine kinase xac1991 SWALL:AAM36853 (EMBL:AE011834) (408 aa) fasta scores: E(): 1.3e-42, 49.49% id in 297 aa, and to Pseudomonas aeruginosa probable two-component sensor pa2571 SWALL:Q9I0R5 (EMBL:AE004685) (470 aa) fasta scores: E(): 1.4e-42, 46.93% id in 326 aa.
 
 
0.914
BPSS1358
Putative sensor kinase protein; Similar to Erwinia chrysanthemi regulator HrpX SWALL:AAM46691 (EMBL:AF448202) (450 aa) fasta scores: E(): 8.4e-24, 28.46% id in 390 aa, and similar to the C-terminus of Pseudomonas aeruginosa probable two-component sensor pa0600 from codon 129 SWALL:Q9I5T8 (EMBL:AE004496) (797 aa) fasta scores: E(): 1.2e-36, 38.79% id in 366 aa, and to similar to the C-terminus of Ralstonia solanacearum probable transmembrane two component system sensor kinase transcription regulator protein rsc0191 or rs00623 from codon 254 SWALL:Q8Y2Z0 (EMBL:AL646057) (458 aa) fasta sc [...]
 
 0.899
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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